The extracellular matrix (ECM) consists of a complex mixture of structural and functional proteins and serves an important role in tissue and organ morphogenesis, maintenance of cell and tissue structure and function, and in the host response to injury. Xenogeneic and allogeneic ECM has been used ...
The extracellular matrix (ECM) consists of numerous macromolecules classified traditionally into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and noncollagenous glycoproteins. In addition to being necessary structural components, ECM molecules exhibit important functional role...
Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which is of great significance to tissue development. ECM in muscle fiber niche consists of three layers: the epimysium, the perimysium, and the endomysium (basal lamina). These three layers of connective...
among which are the matrix metalloproteinases (MMPs) that can proteolytically degrade almost every ECM protein. The membrane bound MT-MMP is a key player in this process, breaking down ECM components
The extracellular matrix of dentin consists of mineral (hydroxyapatite), collagen, and several noncollagenous matrix proteins. These noncollagenous matrix proteins may be mediators of cell-matrix interactions, matrix maturation, and mineralization. This review describes the current knowledge of the chemistry...
The nucleus pulposus (NP) is a gelatinous center-most structure of the intervertebral disc. It is surrounded by concentric layers of annulus fibrosus and sandwiched between cartilaginous endplates. The extracellular matrix of NP consists of collagens and abundant proteoglycans that are bound by sulf...
Regulation of cellular functions by extracellular matrix, which consists of a dynamic assemblage of a variety of interacting molecules capable of reorganization... R Raghow - 《Faseb Journal Official Publication of the Federation of American Societies for Experimental Biology》 被引量: 780发表: 1994年...
TSP5 is found in all cartilages and in the vitreous of the eye, and mutations in the gene cause pseudochondroplasia and multiple epiphyseal dysplasia. TSP5 consists of five disulphide-bonded subunits (each of approximate molecular weight 100,000), which give a molecular mass of 524kDa by ...
The extracellular matrix (ECM) consists of a complex mixture of structural and functional proteins and serves an important role in tissue and organ morphog... SF Badylak - 《Seminars in Cell & Developmental Biology》 被引量: 1783发表: 2002年 The use of extracellular matrix as an inductive sca...
The extracellular matrix (ECM) is one of the major components of tumors that plays multiple crucial roles, including mechanical support, modulation of the microenvironment, and a source of signaling molecules. The quantity and cross-linking status of ECM