Also, a spectrum of vascular changes, including microvascular damage, is known to accompany severe COVID-19. In this paper, we describe the co-occurrence of hemophagocytic lymphohistiocytosis and extensive pulmonary microvascular damage with thrombosis and its sequelae in a patient with fatal COVID-...
CT scans of the head, chest and abdomen showed the following abnormalities: flattening of the paraventricular gyri and reduction of brain parenchyma with hypodensity of the white matter in terms of cortical atrophy; periventricular bilateral small post-ischemic microvascular brain lesions of varying ...
Pro-angiogenic growth factors have been extensively studied in both pre-clinical models and clinical trials to promote the creation of new functional microvasculature and restore perfusion to ischemic tissues5,6,7. However, these therapies are limited in part by protein instability, the inability of ...
While the exact mechanism of development of this cardiomyopathy is unknown, various theories such as catecholamine cardiotoxicity, coronary artery spasm, coronary microvascular impairment, and estrogen deficiency have been proposed One of the most popular theories for the pathophysiological mechanism in the ...
ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress and myocardial stiffening418Investigating the cardiovascular effects of antiretroviral drugs in a lean and high fat/sucrose diet rat model of obesity419Statins in the treatment of non-alcoholic steatohepatitis ...