The journey of modern Homo sapiens began in Africa around 300,000 years ago. This period marks the emergence of anatomically modern humans, who would eventually spread across the globe. Genetic evidence suggests that all non-African populations descend from a small group of individuals who left Af...
findings and reveal that these drastically different metabolic features could, at least in part, due to the weaker abundance of proteins of the two component system PhoR/PhoP inS. coelicolorcompared toS. lividans. In condition of phosphate limitation, PhoR/PhoP is known to control positively and n...
Glioblastoma is the most aggressive primary brain tumor in adults and due to the invasive nature cannot be completely removed. The WNT inhibitory factor 1 (WIF1), a secreted inhibitor of WNTs, is systematically downregulated in glioblastoma and acts as s
18, 27 By analyzing the TCGA database (http://cancergenome.nih.gov/), we confirmed that ADAR1 was elevated in HCC tumor tissues compared with adjacent normal tissues (Figure 3a). Analysis of Oncomine database with results obtained from different groups also supported this conclusion (...
MAOA, childhood maltreatment, and antisocial behavior: meta-analysis of a gene-environment interaction. Biol Psychiatry 2014; 75: 9–17. Article CAS Google Scholar Haberstick BC, Lessem JM, Hewitt JK, Smolen A, Hopfer CJ, Halpern CT et al. MAOA genotype, childhood maltreatment, and their ...
In angiosperms the reproductive transition results in the transformation of a vegetative apical meristem (SAM) into an inflorescence meristem (IM), capable of forming floral meristems (FM). Two key players in the flowering transition are AGAMOUS-like 24 (AGL24) and SHORT VEGETATIVE PHASE (SVP)....
Despite the potential of the endoplasmic reticulum (ER) stress response to accommodate adaptive pathways, its integration with other environmental-induced responses is poorly understood in plants. We have previously demonstrated that the ER-stress sensor
An image of the network graph is shown in Figure 3 with annotation of clusters of interest highlighted in distinct colours. The entire dataset is available on http://www.macrophages.com/hu-cell-atlas, where a webstart version of BioLayout Express3D enables visualisation of the average expression...
High transposase expression in Baltic Sea bacteria T Vigil-Stenman et al Conflict of Interest The authors declare no conflict of interest. Acknowledgements We thank BalticSea2020 and the Olle Engkvist Byggmäs- tare Foundations for financial support, Science for Life Laboratory and Uppmax for ...
expression of each gene (Supplementary Data3). SNPs located within the same genome as a gene of interest were referred to ascis-genomic SNPs, whereas SNPs located in other genomes were referred to astrans-genomic SNPs (Fig.2a). For the 10,000 most highly expressed genes, the mean of gene...