Because low glutamate level brings the transamination reaction closer to thermodynamic equilibrium, an accompanying upregulation of alaC might provide the necessary enzymatic capacity36. The last new interaction is DhaR and DHAP, a regulator of dihydroxyacetone kinases, which seems to activate in ...
23). The spread of expression levels of motif-associated genes was over 2.5-fold larger than its expected (median) expression level (Supplementary Fig. 24), resulting in a low median SNR of under 0.4 (Fig. 4a). Of the full 4 order-of-magnitude range of gene expression levels observed ...
Gene expression was quantied as transcripts per million (TPM) and log2-transformed (Goldman et al., 2020). A gene expression level is presented as low/medium/high depending on the expression level of a such gene in patients of the reference cohort. Low = < 17%; Medium = 17%-83%; ...
Tissue Enriched:Genes with an expression level greater than or equal to 1 (TPM or FPKM) that also have at least five-fold higher expression levels in a particular tissue compared to all other tissues. Group Enriched:Genes with an expression level greater than or equal to 1 (TPM or FPKM) ...
The high expression level in normal skin possibly contributes to the cutaneous toxicity associated with enfortumab vedotin approval and requires careful consideration as ADCs targeting Nectin-4 are developed to target breast cancer. 展开 关键词: 4 1 ...
RNA-seq of SUN5 analysis revealed an average expression level of 2003 and a TPM value of 49.8. Full-length CDS of SUN5 was 1152 bp long, encoding 383 amino acids. Compared to the swine (Sscrofa11.1) genome sequence, the SUN5 gene in BMI had an insertion of three bases GAA at 469...
Findings obtained from this study showed that Fusarium isolates that cause head blight and crown rot in Turkey have a low level of variation in terms of phenotype and genetic characteristics. Moreover, this is the first report to show that TPM led to a potential decrease in toxin production-...
In general, the expression levels related to 77% of these genes are in line with the results of differential expression analysis, which reflects the reliability and reproducibility of the results of the present study. In addition, the expression level of hub genes and TFs was compared with the...
We show in humans that majority (~78%) of the RBPs are strongly associated with their target transcripts at transcript level while ~95% of the studied RBPs were also found to be strongly associated with expression levels of target transcripts when protein expression levels of RBPs were ...
Circular RNAs (circRNAs) are emerging as novel regulatory RNAs that have been found in various tissues and cell types. Notably, circRNAs are enriched and stable in whole blood, platelets, and exosomes, which makes circRNAs in human peripheral blood good candidates for diagnostic or prognostic biomar...