Expression of the VDR is regulated by external stimuli in a tissue-specific manner. However, the mechanisms of this tissue-specificity remain unclear. Studies also suggest that phosphorylation of hVDR at serine 208 impacts the receptor's transcriptional activity. These experiments were conducted in ...
PIKEPIK3CAGlioblastomas frequently carry genetic alterations resulting in an aberrant activation of the phosphoinositol-3-kinase (Pi3k)/protein kinase B (Akt) signalling pathway, including most notably phosphatase and tensin homolog (PTEN) mutation, epidermal growth factor receptor (EGFR) amplification ...
Background Accurate protein quantification is a vital prerequisite for generating meaningful predictions when using systems biology approaches, a method that is increasingly being used to unravel the complexities of subcellular interactions and as part of the drug discovery process. Quantitative proteomics, ...
Hierarchical clustering of HLRCC renal tumors and normal kidney based on the expression levels of ribose sugar metabolism genes.Youfeng, YangAndrew N., LaneChristopher, J. RickettsCarole, SourbierMingHui, WeiBrian, ShuchLisa, PikeMin, WuTracey, A. Rou...
Cheah, Pike-SeeSzarek, EvaBanerjee, KakoliSchwartz, JeffreyThomas, PaulESGene Expression PatternsRogers N, et al. 2013. Expression of the murine transcription factor SOX3 during embryonic and adult neurogenesis. Gene Expr Patterns 13(7):240-248....
The osteocalcin gene promoter as a molecular model for determining tissue-specific expression and hormonal regulationPike, J. W.Kesterson, R. A.Kerner, S. A.EXCERPTA MEDICA INTERNATIONAL CONGRESS SERIES
Endocrinology and Metabolism Clinics - Vol. 39 - N° 2 - p. 255-269 - Iconography : The Vitamin D Receptor: New Paradigms for the Regulation of Gene Expression by 1,25-Dihydroxyvitamin D 3 - EM|consulteJ Wesley PikeMark B MeyerElsevier Masson...
Expression of the lymphotoxin β receptor on follicular stromal cells in human lymphoid tissues. Murphy M,,Walter BN,Pike-Nobile L, et al. Cell Death and Differentiation . 1998Murphy,M,Walter,BN,Pike-Nobile,L,Fanger,NA,Guyre,PM,Browning,JL,Ware,CF,Epstein,LB.Expression of the lymphotoxin ...
PikeOverzetKarinvan de VenBrittHoeke, G.; Khedoe, P.; van Diepen, J.A.; Pike-Overzet, K.; van de Ven, B.; Vazirpanah, N.; Mol, I.; Hiemstra, P.S.; Staal, F.J.T.; Stienstra, R.; et al. ...
Allelic, or haplotype, exclusion of immunoglobulin gene expression ensures that the products of a single allele or light chain isotype are expressed on the B cell surface. Evidence has accumulated in rodent and primate models to indicate that the products of successful rearrangement regulate this ...