Gene expression involves transcription, translation and the turnover of mRNAs and proteins. The degree to which protein abundances scale with mRNA levels and the implications in cases where this dependency breaks down remain an intensely debated topic. H
The role of regulatory variation in complex traits and disease. Nat. Rev. Genet. 16, 197–212 (2015). CAS PubMed Google Scholar Babu, M. M., Luscombe, N. M., Aravind, L., Gerstein, M. & Teichmann, S. A. Structure and evolution of transcriptional regulatory networks. Curr. Opin....
Tissues of mice in the control and 2 h post-exposure groups were removed for detection of mRNA expression of Pit1 and Pit2. To prepare the STZ-induced diabetic mouse model, 24 mice, weighing 17-19 g, were fasted for 12 h with free access to water, and then fasting blood glucose ...
When visualizing the structure of an expression tree, it’s useful to focus on these two properties, as depicted inFigure 3. Figure 3 NodeType, Type, Value and Name Properties If there are no public constructors for these types, how do we create them? You have two...
The M'zab architecture, located in M'zab valley that is known for its a unique geographical and cultural worth, has preserved its identity embodied in its typology, participatory paradigm; and site as well as its social realities. Even more; the newly built ksurs are designed to meet the ...
Transgene Expression in Plants , Control of Definition of the Subject To define the subject in relation to the title, we would like to emphasize that most of the results and conclusions described below were obtained in the model plantsArabidopsis thalianaandNicotiana tabacumafterAgrobacterium-mediated ...
The combination of promoters controlled by one lacO site and lacIQ repressor (Fig. 3d, g) and the T7 expression system (Fig. 3h) resulted in the desired system properties, including tunability and low system leakiness. Fig. 3 Influence of lac operators on expression rate control, shown by...
Once that happens, the ⌈o⌋ is checked against the next character, and if it matches, control moves to the next component. In this case, the “next component” is ⌈(nite|knight|night)⌋ which really means “⌈nite⌋ or ⌈knight⌋ or ⌈night⌋.” Faced with three ...
Immunofluorescence was used to observe and evaluate the markers of mucous secretion—Mucin 5AC(MUC5AC) and the markers of ciliary structure—acetylated alpha-tubulin(acet. α-tubulin) at the protein level. Results Compared with those in the control group, the total fluorescence intensity(TFI) of...
3C), suggesting that these sequences constitute alternative splice donor sites (DS1) that can be used in place of the donor sites located at the 3′-border of these elements (DS2). Nothing is known at present about the control of this splice donor site usage and the underlying mechanism....