Influenza A and B, adenovirus, respiratory syncytial virus (RSV), parainfluenza. Table 4.Risk factors related to specific pathogens in community-acquired pneumonia (Mandel et al., 2007) AlcoholismStreptococcus pneumoniae, oral anaerobes,Klebsiella pneumoniae,Acinetobacterspecies, Mycobacterium tuberculosis ...
Studies “Duke” and “UVA” challenged participants with HRV, while ”DEE1” challenged individuals with RSV. In all cases, individuals had blood samples taken at regular intervals every 4–12 h both prior to and after infection; see Fig. 1 for details. Specific time points are measured as...
When RSV associated with PM10 comes into contact with respiratory epithelial cells, there is a greater increase in the secretion of inflammatory mediators (IL-6 and IL-8) compared to infection without PM1028. Other studies report that PM2.5 can induce epigenetic changes through microRNA ...
Finally, Experiments 6 and 7 investigate how the feature selection process may depend on exclusion or inclusion of the same viral pathogen during the feature selection. Experiment 6 includes all non-RSV studies as part of the feature selection, and studies performance with the DEE2 study. Experime...
Maternal vaccination has emerged as a promising strategy, delivering elevated antibody levels to newborns for immediate protection. However, limited research has explored the protective efficacy of maternal antibodies (matAbs) against secondary RSV infections in offspring. To address thi...
Robrsv(iFoiugs. a3tbt,hpe 0.05, n = 5–11/group) and co-exposures evaluation of the lungs from SOA-exposed wwietrheOsi3manildar/otroNthOe2c(oFnigtr. o5lbF; pA >-e x0p.0o5s,end =, s 5h–o1w1i/nggronuopi)n. Hflaismtomloagtiocr...
IL22 plays an important role in epithelial repair following injury aiding in epithelial cell proliferation inducing anti-apoptotic peptides and cytokines, reducing inflammation, and, at least against RSV, demonstrating anti-viral activity [27, 28, 52,53,54]. In addition, data suggest that IL22 ...
Furthermore, treatment of RSV-infected mice with ultrafine carbon black enhances the expression of various chemokines that are associated with virus infection, and leads to an enhanced RSV-induced airway hyperresponsiveness to methacholine [51]. In this paper, we show that NP exposure of persistently...
Cells (6 × 105 cells/well) were seeded into six-well cul- ture plates (VWR, Ismaning, Germany) and were incubated at 37 °C, 5% exposed to 100, 200, 500 or 5000 rESWs using the handpiece of a radial eCxOtr2afcoorrpanoorethalesrh2o4c hkowuarsv.eTdheevciceell...
A recent clinical study using small inhibitory RNA complimentary to the mRNA encoding respiratory syncytial virus (RSV) protein demonstrated feasibility and potential efficacy of delivering small RNAs directly to the airway mucosa (Zamora et al., 2011). Human miRNAs with antiviral effects thus have ...