The objective of this study is to investigate the role of sinomenine (SIN) on sepsis-induced MI and clarify the underlying mechanism based on the techniques of network pharmacology. Methods: Cecum ligation and puncture (CLP) was adopted to induce sepsis in male Sprague-...
(PAN) was inserted just upstream of the SIVnfl insert. In vector 5, the SIV promoter/enhancer region was used by restoring nucleotides 1C521 of the 5 LTR. These three promoters were used in combination in an attempt to achieve stable expression of SIVnfl during all stages of the RRV life...
explore_underlying_mechanism_binary_security.zip虞女**女祠 上传2.11 MB 文件格式 zip 探究底层机制:二进制安全 点赞(0) 踩踩(0) 反馈 所需:1 积分 电信网络下载 FM 2025-01-14 14:28:41 积分:1 SmartFm 2025-01-14 14:28:11 积分:1 ...
Curcuma has been used as an adjuvant treatment for osteosarcoma (OS) due to its anticancer compounds. However, the underlying mechanism remains unclear. Therefore, this study aimed to explore the mechanism of action of curcuma in the treatment of OS usin
organism and response. The theory points out that the external environment incentive can stimulate the inner or perceptual state of the individual user, and then drive the individual behavior response. SOR serves as a research framework for exploring the underlying mechanisms of conceptual connections ...
Identifying underlying mechanisms of tumor growth Historically, glioblastoma's poor response to treatment has been attributed to intratumor heterogeneity and evolution, which helps the tumor resist treatment, which includes surgery followed by a combination of aggressive chemotherapy and radiation. ...
This study aims to uncover the potential therapeutic effect of nomilin on TNBC and elucidate the specific mechanism of its action. Methods We employed weighted gene co-expression network analysis (WGCNA), differential expression analysis, and the GeneCards database to identify potential targets for ...
However, little is known about its underlying mechanism. Herein, an integrated approach combining multiplatform-based metabonomics and network analysis was adopted to elucidate the ameliorative mechanism of HZ on hyperlipidemia. The global metabolomic characters of HZ on hyperlipidemia were investigated by ...
The networks revealed that BSTZC was associated with the treatment of HLP through multi-targets and multi-pathways, we speculated that the underlying mechanism of BSTZC was probably related to its regulation of several biological. Figure 7 (A) Bubble chart of gene ontology (GO) function ...
(Extended Data Fig.7d–g). This trend of decreased kurtosis in the face of increased noise variance captures the widespread observation that, in animals, the velocity statistics tend towards a Gaussian distribution as sensory salience is decreased. Moreover, the underlying mechanism, namely, ...