molecular docking is utilized for compound assessment, which can also be replaced by shape-/pharmacophore-based evaluation methods. In the genetic selector module, a genetic algorithm is used given the similarity between the triage strategy of fragment growing and the genetic rule “fitness to surviv...
which are a rapidly emerging global health challenge. However, our understanding of the structure-function relationships of AMPs is limited, and we are just beginning to rationally engineer peptides in order to develop them as therapeutics. Here, we leverage...
Key words DSS, Web-based data mining exploration, Decision trees, Clustering, Association rules 1 Introduction During the last decade, use of data mining in organizations has expanded significantly since the data mining methods can be accepted commonly as a useful tool for decision-makers in ...
Methods for anomaly detection, including novelty detection and outlier detection, have been surveyed extensively (Markou and Singh2003a,b; Marsland2003; Hodge and Austin2004; Agyemang et al.2006; Modenesi and Braga2009; Chandola et al.2009; Pimentel et al.2014). While outlier detection approaches ...
Despite this well-known documented fact, most microbiology isolation and cultivation efforts remain heavily dependent on the classical methods, with reliance on agar-based homogeneous media that share little resemblance with the complexity of the natural environment. The advent and widespread use of molec...
Therefore, this study aimed to describe the persecution experiences of gay and bisexual asylum seekers and refugees in the Nairobi Metropolitan Area. Methods: We adapted McAdam's Life-Story Interview (LSI) to develop a semi-structured interview guide. We used the interview guide to conduct one-...
Laboratory “Hybrid Methods of Modelling and Optimization in Complex Systems”, Siberian Federal University, Prosp. Svobodny 79, 660041 Krasnoyarsk, Russia 9 Institute of Informatics and Telecommunications, Reshetnev Siberian State University of Science and Technology, 31 Krasnoyarskiy Rabochiy Av., 66003...
The phenomenon of workplace involution has attracted ample attention. How to make employees treat their work with the correct attitude and behavior and improve their work performance has become a realistic proposition. This study uses a combination of qualitative and quantitative research methods, with...
20 h of interactive interviews were analyzed by using qualitative methods. Emerging themes include how MTEs establish a sense of credibility and how they feel they are navigating multiple identities. Among the graduate MTEs, credibility was described as having the following: (a) knowledge of and ex...
2. Materials and Methods Our study availed the opportunity presented by the qualitative arm of 15 year follow up of the Maternal and Infant Nutrition Interventions in Matlab trial (MINIMat, ClinicalTrials.gov identifier ISRCTN16581394), which was a randomized supplementation trial initiated in Matlab...