The primary structure is based on the amino acid sequence in a polypeptide chain linked by a peptide bond. They are constructed of a set of 20 amino...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can a...
P and N nucleotides are most responsible for the appearance of TCR, or the chains of the amino acid which are not encoded by the germline. Nucleotides...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your ...
Explain the process of protein synthesis from mRNA to protein. Why DNA is transcribed into mRNA to synthesize proteins? Explain. Discuss in detail amino acid synthesis and degradation and how they relate. Are amino acid produced via transamination and dea...
Comparing to a generic two-state model, our models can distinguish class I from class II MHCs and correlate their structural parameters with the TCR/pMHC’s potency to trigger T cell activation. The models are tested by mutagenesis using an MHC and a TCR mutated to alter conformation changes....
Missense mutations:This point mutation results in the replacement of one nucleotide by another. In some cases, this change causes a change in the amino acid encoded, which may or may not have an impact on the function of the protein produced by the gene in the case of a gene encoding, ...
Immunohistochemical stains demonstrate an acinar cell defect but normal islet cells. Mammalian genomes contain two Sec23 paralogs, Sec23A and Sec23B. The encoded proteins share ~85% amino acid sequence identity. We generate mice with pancreatic SEC23A deficiency and demonstrate that these mice survive...
(2003) How can free energy component analysis explain the difference in protein stability caused by amino acid substitutions? Effect of three hydrophobic mutations at the 56th residue on the stability of human lysozyme. Protein Eng., 16, 665-671....
What is the general/generic formula for carbohydrates? (a) Describe the structure of carbohydrates, lipids, and proteins. (b) Give an example of each. What are the classes of carbohydrates? Explain why carbohydrates and lipids are high-energy molecules. What is the ultimate source of all ...
Describe the genetic code and how the nucleotide sequence determines the amino acid and the protein sequence. How can the structure and function of nucleotides (DNA and RNA) allow the cell to assemble specific proteins with different structures and functions?
Explain the role of the liver in the formation of urea.Question:Explain the role of the liver in the formation of urea.Human Anatomy:Human anatomy is the study of the structure and organization of the human body. It is a branch of biology that deals with the physical and functional charact...