Actin depolymerization factors (ADFs) are among the most important actin regulators, affecting the rates of filament turnover in a multifaceted manner. Plasmodium has two ADFs that display low sequence homology with each other and with the higher eukaryotic family members. Here, we show that ADF2...
Explain the structure of muscle. Start with the epimysium and finish with the sarcomere. What is a sarcomere? Explain the structure of the sarcomere and how actin and myosin cause a contraction. What is the function of ATP in skeletal muscle?
Describe the structure and function of a muscle fiber; summarize the process of muscle contraction. (a) Describe the structure of the actin filament. (b) Describe its function. (a) Describe the structure of the chromosomes. (b) Describe its function. (a) Describe the structure of the ...
These experiments produced different results for the isolated N-TnC compared with experiments that include the cTn complex and cardiac thin filament proteins actin and tropomyosin (19, 20). By understanding the thermodynamic basis of the function of N-cTnC, we can explain this variation and explore...
Actin depolymerization factors (ADFs) are among the most important actin regulators, affecting the rates of filament turnover in a multifaceted manner. Plasmodium has two ADFs that display low sequence homology with each other and with the higher eukaryotic family members. Here, we show that ADF2...
There are no amino acid changes between the chicken and human skeletal muscle isoforms, and the most dissimilar actins still share more than 85% sequence identity [1]. We suggest that large discrete internal modes of freedom within the actin filament [2] may account for a significant component...
Using example, explain how the structure of the muscle tissue allows them to carry out their functions. Explain the sliding filament mechanism of muscle contraction. When muscle tissue dies, it usually is replaced with dense irregular collagenous connective tissue. ...
Explain the structure of muscle. Start with the epimysium and finish with the sarcomere. What is a sarcomere? Explain the structure of the sarcomere and how actin and myosin cause a contraction. Explain one disorder of the muscular system. ...
Describe how actin and myosin work in conjunction with each other to power movement in skeletal muscle. How does muscle fiber structure relate to muscle contraction? Explain the mechanics and energetics of how myosin "walks" along a thin filament. How does the sliding of filaments cause a muscle...
A motor unit is an alpha motor neuron and all of the fibers that it innervates. They can be very small, only innervating 2-10 muscle fibers such as in the ocular muscles, or very large up to thousands of fibers in the quadriceps muscles. Interestingly, the amount of muscle fibers t...