In the present work, by means of a mathematical model, we investigated the mechanism of the activation of contact pathway of blood plasma coagulation. The model describes membrane-dependent reactions of the activation of factors XII and XI with account of the presence of blood plasma inhibitors. ...
That is, as HPV normally involves a local feedback mechanism whereby pulmonary arterioles constrict in response to poor regional oxygenation12, a failure of this response could potentially lead to a significant mismatch between ventilation and perfusion13. Impaired HPV is not the only possible ...
The responsible mechanism is still uncertain; it may involve one or more of four possible fibrinogen functions: as the precursor of fibrin in clotting; as an essential co-factor of platelet aggregation; as a factor in rouleaux formation of red cells; and through increasing plasma viscosity. ...
Also the mechanism of acute myocardial injury caused by SARS-CoV-2 during severe COVID-19 disease might be related to the inhibition of the ACE2 catalytic activity [37]. Humans are not equal with respect to the expression levels of the cellular ACE2 enzyme and ACE2 gene expression and/or...
94. Pharmacological remodeling of platelet-rich clots architecture by ABCIXIMAB (C-7E3) may explain the mechanism of its curative antithrombotic effectAn abstract is unavailable. This article is available as a PDF only.doi:10.1097/00001721-199810000-00114Collet, J. P....
BLOOD coagulation disordersTo evaluate the haematological findings of patients with severe acute respiratory syndrome (SARS).Analysis of the demographic, clinical, and laboratory characteristics of patients with SARS.Prince of Wales Hospital, Hong Kong.All patients with a diagnosis of SARS between 11 ...
The complete pathophysiological mechanism of the increased risk of venous thrombosis (VT) after air travel is unclear. Although immobility undoubtedly plays a major role, it was recently shown that clotting activation occurs more often during air travel than during immobilized or ambulant circumstances ...