Describe the basis for adverse drug reactions in patients with end-stage renal disease. What causes hypovolemic shock to develop with intestinal obstruction? a. continued vomiting and fluid shift into the intestine b. hemorrhage into the intestine c. rupture of...
Medication useAims: Recently, an increase in the incidence of end-stage kidney disease (ESKD) among people with type 2 diabetes (T2D) aged 80 years has been observed in Australia. We examined whether patterns of medication use are likely to explain these trends.Buyadaa, OyunchimegKoye, Dig...
(ACE1), have been associated with numerous comorbidities, such as cardiovascular disease, hypertension, diabetes, chronic kidney disease, and obesity, and there are potential mechanisms to explain these associations (e.g., DD-type carriers have greater ACE1 activity, and patients with a genetic ...
Humans cannot survive if their bodies are lacking the ATP7A gene, yet children can develop Menkes disease when the gene is mutated or missing. Previously, scientists did not have a good model to test the gene's function or develop an understanding of the underlying causes of the disease sympt...
Their clinical presentations varied from early-stage to widely metastatic disease, and included three cases of non-Hodgkin lymphoma, one case of Hodgkin lymphoma, one of anal cancer, one of colorectal cancer, one of neuroendocrine origin, and one of acute T-cell lymphoblastic leukemia. All of ...
Describe the basis for adverse drug reactions in patients with end-stage renal disease. Can gene therapy be used for purposes other than the treatment of "monogenic" diseases (e.g., cystic fibrosis)? Explain. Describe how family characteristics influen...
The mechanism of human immunodeficiency virus 1 (HIV-1) nuclear entry, required for productive infection, is not fully understood. Here, we report that in HeLa cells and activated CD4+ T cells infected with HIV-1 pseudotyped with VSV-G and native Env pro
Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease. Kidney Int. 2010, 78, 975–980. [CrossRef] [PubMed] 73. Rosen, C.J. Vitamin D insufficiency. N. Engl. J. Med. 2011, 364...
Serious lupus nephritis is treated aggressively because it can progress to end-stage kidney disease (ESKD). End-stage kidney damage from SLE requires dialysis and/or a kidney transplant. Rarely, people with SLE can develop seriously low platelet levels, thereby increasing the risk of excessive and...
A third of ARPKD patients die in the perinatal period, and those surviving the neonatal period commonly develop end-stage renal disease ( ESRD ) in infancy, early childhood, or adolescence. Some patients are first diagnosed as adults. While bilateral renal enlargement with microcystic d...