The TCR integrates forces in its triggering process upon interaction with pMHC. Force elicits TCR catch-slip bonds with strong pMHCs but slip-only bonds with weak pMHCs. We develop two models and apply them to analyze 55 datasets, demonstrating the models’ ability to quantitatively integrate and...
Many of the observations shown in Fig.1can be directly explained by the proposed source models, controlled by spatiotemporal stress perturbation introduced by fluid transfer. For example, parallel normal and thrust faulting at the North Mid Atlantic Ridge (Fig.1a) have been explained in response t...
Models Fig. 2: Proposed conceptual models for anti-repeating events. Full size image Dike intrusion and growth Trapdoor faults Ring faults Dike-parallel joints Overshooting Fluid injection Discussion Fig. 3: Synthetic tests. A comparison of minimum and maximum CC for synthetic waveforms of 3000 rando...
(A) In a single-processor multiprogramming system, processes are interleaved in time to yield the appearance of simultaneous execut True or false? A technique in which one system models the behavior of another system is called a simulation. In what type...
All models have good stereochemistry, as determined by the program PROCHECK (44). Refinement statistics are given in Table 1. The Kabsch and Sander algorithm as implemented in DSSP was used for secondary structure assignment (45). Structural alignments were carried out with the programs TOP (46...
Our departure point is the model by Jackson and Rogers27, in which 'role models' in a network introduce their new contact to their other contacts. This model can reproduce many attributes of large-scale human social networks. Similar models reconstruct the structure of other systems, such as ...
As shown in Figs. 7e and f, there is a particularly striking correspondence between the faults and cracks generated in our DEM models and those observed in the emergent Mount St. Helens 2004 spine 3. In all the models, the magma ascending past the shrinking conduit is fractured by ...
and models their effects on haplogroup diversity in males given different levels of patrilineality, in a population divided into sociocultural groups that are equivalent to ‘tribes’. The model is comprised of a male population subdivided into cells in a grid of cultural groups, or ‘tribes’ ...
voids inside the various membranes, we have developed an algorithm to ''map'' such voids in three dimensions (see Computational methods). This allows us to plot the profiles of free volume depending on the Z coordinate in the membrane (Z is the distance from the membrane's middle plane)....
Our departure point is the model by Jackson and Rogers27, in which 'role models' in a network introduce their new contact to their other contacts. This model can reproduce many attributes of large-scale human social networks. Similar models reconstruct the structure of other systems, such as ...