When a cell divides, it must reproduce its DNA so that each cell that results from the division has the samegenetic code. That means it must replicate its DNA. During this process, an enzyme called a helicase separates the two strands, breaking the hydrogen bonds between the A - T and G...
How to cite this article: Maleki, S. et al. Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves. Sci. Rep. 6, 35712; doi: 10.1038/srep35712 (2016). References Laforest, B. & Nemer, M. Genetic insights into bicuspid aort...
The first mechanism, leading to strong correlations between clades of Y-chromosomes and sociocultural groups, produces population structure through a culturally transmitted ideal. The second mechanism describes how such structure interacts with competitive social dynamics to affect the genetics of populations...
However, in the early 1990s, Lupski was one of the early champions of a newly discovered mechanism in which the structure of the DNA itself was grossly duplicated or deleted to change numbers of copies of a gene that occurred in the genetic material. This "copy number variation" wrote a ...