Explain the origin of chemical shift in NMR spectra. Choose one famous atomic scientist. Describe their discovery and explain how the discovery was made. Explain why different elements produce different colors of light when heated. Explain in detail when a metal reacts with an acid, hydrogen gas...
The second set of studies examined a hybrid TCR with the mouse 2B4 Vαβ fused with the human LC13 Cαβ and 4 double mutations on the Cβ domain, which have been indicated by our previous NMR and chemical shift experiments38 and by recently published cryoEM structures43,44 to impact it...
these two mechanisms give rise to a catch-slip bond. Upper: Schematics of the TCR–pMHC-І structure (left) and its conformational changes that correspond to low (middle) and high (right) forces. Note that in the lower panels of both (a,b), the energy wells in the absence and presen...