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Model fitting to experimental data was done by nonlinear curve-fitting in the least-squares sense using the Levenberg-Marquardt algorithm (MATLAB built-in function). Briefly, the best-fitting parameter set was derived by fitting model to mean value of bond lifetime vs force profile, and SE of...
Mixtures of Gaussians and the EM algorithm Mixtures of Gaussians Note that if we knew what the z(i)’s were, the maximum likelihood problem would have been easy. Specifically, we could then write down the likelihood as: &nbs...
@inproceedings{lengerich2020purifying, title={Purifying interaction effects with the functional anova: An efficient algorithm for recovering identifiable additive models}, author={Lengerich, Benjamin and Tan, Sarah and Chang, Chun-Hao and Hooker, Giles and Caruana, Rich}, booktitle={International Confere...
But guess what, I’m not going to use words like algorithm or consensus in this article. I’m going to attempt to explain what Delegated Proof of Stake (DPOS) is in such a way that anyone, even a 5 year-old could understand it. Why Was Delegated Proof of Stake Invented? A block...
First things first, a little bit of theory. I won't go deep into quantum mechanics now (primarily because I don't understand it well enough to talk about it in public). What we really need to know about emulating a quantum computer, is that it's all about matrix multiplication. Quantum...
Describe an algorithm in pseudocode that returns the sum of positive integers (a1, a2, ..., an) in a list. 1. Write a recursive program that calculates m to the nth power. Instead of iteratively multiplying m n times, you will compute the result recursively by performing successive multipl...
In most organisms, the number and distribution of crossovers that occur during meiosis are tightly controlled. All chromosomes must receive at least one ‘obligatory crossover’ and crossovers are prevented from occurring near one another by ‘crossover
Explain to The Algorithm of Image Processing Edge detection An edge is the boundary between two regions with relatively distinct gray-level properties. Most edge detection techniques is the computation of a local derivative operator. Edge detection provides post processing with meaningful information. Exp...
More recently, series are used which operate on similar principles but converge even more quickly. The latest computer record used the 1989 Chudnovsky algorithm, which is based on the series: In 2011 Shigeru Kondo set this record on a custom-built home computer using y-cruncher, a program writ...