189]. Recent studies have shown that CAR-T cell-derived exosomes as a cell-free therapy not only retain most of the functions of CAR-T cells but also have greater therapeutic efficiency, higher controllability, lower toxicity, and
including all areas of exosome production, such as methods for exosome separation, quantification, and characterization. The standardized and simplified preparation processes in large-scale exosome production are key to the reproducibility of exosome therapy product results in preclinical and clinical settings...
Exosomes with the ability of vesicle-mediated intercellular signal transmission have gained worldwide attention and can achieve cell-free therapy. Exosomes are small vesicles that are secreted by cells, which contain genetic material, lipids, proteins and other substances. It has been found to play ...
Open AccessReview by Marina Elkommos-Zakhary 1,†, Neeraja Rajesh 1,†and Vladimir Beljanski 1,2,* 1 Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Davie, FL 33314, USA 2 Cell Therapy Institute, Nova Southeastern University, Davie, FL 33314, USA ...