Exosome Diagnostics partners with biopharma companies and Clinical Centers of Excellence to facilitate biomarker discovery programs in support of early discovery, translational, and clinical programs that may h
Raimondo F, Morosi L, Chinello C, Magni F, Pitto M: Advances in membranous vesicle and exosome proteomics improving biological understanding and biomarker discovery. Proteomics 2011;11:709-720.Raimondo F, Morosi L, Chinello C, Magni F, Pitto M: Advances in membranous vesicle and exosome ...
Endogenously tagging EV's with luciferase to track their biogenesis, function, and intercellular communication. AAVS1 SparQTM All-In-One Inducible System Precision Gene Modulation at Targeted Site in Mammalian Cells. SmartSEC™-TC Single-Fraction Elution EV Isolation Kit for Tissue Culture Media Sm...
The discovery of their function in genetic exchange between cells has brought increasing attention to exosomes. MicroRNAs are a class of 17–24 nt small, noncoding RNAs, which mediate post-transcriptional gene silencing by binding to the 3′-untranslated region (UTR) or open reading frame (ORF)...
Exosomes’ primary function is to mediate near and long-distance intracellular communication, by transporting their cargo of nucleic acids, proteins, lipids, amino acids, and metabolites, reflecting their cell of origin. Exosomes are being investigated for the key roles they play in the following pro...
(See a complete list of products discussed in this article.) Exosomes are small (30–150 nm) vesicles secreted by mammalian cells that, along with their unique RNA and protein cargo, have become the focus of much...
The exosome approach to biomarker discovery and development has distinct advantages over other liquid biopsy methods like ctDNA and CTCs. Exosomes are the platform to find clinical utility in diverse disease areas, including: Oncology Neurodegenerative Disorders Cardiology Immunology and Inflammation Patented...
Endogenously tagging EV's with luciferase to track their biogenesis, function, and intercellular communication. AAVS1 SparQTMAll-In-One Inducible System Precision Gene Modulation at Targeted Site in Mammalian Cells. SmartSEC™-TC Single-Fraction Elution EV Isolation Kit for Tissue Culture Media ...
Exosomes are excreted to the extracellular space and function in local and systemic cellular communication. Based on their primary origins, they can contain substantial amounts of RNA, protein, and miRNA; the horizontal transfer of these contents significantly determines the exosome's biological effects...
The index n refers to the nth non-trivial zero of the Bessel function. The high-frequency oscillation of the membrane at 6250 Hz by piezoelectric transducer has a (0,4) vibration mode, while the low high-frequency oscillation of the membrane at 200 Hz by vibration motor has a (0,1...