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METHODS: In a multicentre study, we collected data on 113 pregnancies occurring in 81 women with pre-existing biopsy-proven LN. Primary outcomes were fetal loss including perinatal death and renal flares during and 12 months after pregnancy. Univariate and logistic regression analyses were used to ...
Following severe cases of disease occurring in the Africa continent, OpenWHO offered an Introductory course on Rift Valley Fever in English and French in 2017. For this course, Saudi Arabia was the second country by enrolments (4.51%). This introductory RVF course had larger numbers of users ...
wall thickness, or the presence of a pericardial effusion occurring or changing during pregnancy. In women with established heart disease, in particular those with congenital heart disease, repeat
The encoding session was partitioned into blocks (of about 50 s), with the two presentations of an object–word pairing occurring always within a minute, i.e. either in the same block, or, when the first presentation was in the second half of a block, the repetition occurred in the ...
In this review we focus on adeno-associated virus-based gene therapies, describing the immune response that occurs to naturally occurring adeno-associated viruses, the implications for patients with this exposure, the assays used to detect preexisting immune responses, and strategies to circumvent pre...
Similarly, disorders occurring with sex-unique physiologic states, such as pregnancy, polycystic ovarian disease, and menopause, have been observed to be associated with increased CV risk, but they are under-researched and mechanisms have not yet been elucidated. Despite well-known sex differences in...
Pre-existing antibodies (pre-Abs): Antibodies reactive with the biologic drug that are present in subjects before treatment (or before initiation of the clinical study) (22). These are naturally occurring or otherwise endogenous antibodies to a variety of proteins and glycans that cross react with...
Up to 13 percent of women have some form of hypertension during pregnancy. Seventy percent of hypertension during pregnancy is due to physiological changes occurring during pregnancy andblood pressurereturns to normal after delivery. Five to seven percent ofpregnant womendevelop a life-threatening condit...
not, occurring in 30.2% vs. 37%, respectively. When looking at each outcome individually, antihypertensive treatment significantly lowered the risk for preeclampsia and birth before 35 weeks. The rates of placenta abruption and fetal or neonatal death were not significantly different between the ...