About 30% of patients with RA show inadequate response to the first biologic therapy, which is usually a tumour necrosis factor (TNF) blocker, currently considered with methotrexate (MTX) as the 'gold standard' in RA therapy. After failure of at least one TNF inhibitor, the response rate of...
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Targeted Therapy: The discovery of the Philadelphia chromosome and the BCR-ABL fusion protein has revolutionized the treatment of CML and Philadelphia chromosome-positive ALL. Targeted therapy drugs like tyrosine kinase inhibitors (TKIs) specifically inhibit the activity of the BCR-ABL fusion protein, ...
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Treatment of breast cancer may involve surgery, radiation, hormone therapy, chemotherapy, and targeted therapy. Breast cancer risk may be lowered by managing controllable risk factors. Osteoporosis Osteoporosis is a condition characterized by the loss of bone density, which leads to an increased risk ...
To estimate prognosis:In some cases, higher levels of a particular tumor marker may indicate a poorer prognosis. To determine treatment choice:Gene mutations and other genomic alterations may be used to determine if targeted therapy is indicated, to learn if resistance to targeted therapy has develo...
Oligonucleotide synthesis is the chemical process by which nucleotides are specifically linked to form a product of desired sequenced.
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Developed a patient education programme that increased patient engagement and adherence to treatment plans by over 35%, enhancing the overall effectiveness of therapeutic interventions. Played a pivotal role in the research and implementation of a new targeted therapy treatment, which has since become st...