作为激酶抑制剂的杂环化合物 Examples of the heterocyclic compound kinase inhibitors本发明涉及式(I)的新化合物,其能够抑制一种或多种激酶,尤其抑制SYK(脾酪氨酸激酶),LRRK2(富亮氨酸重复激酶2)和/或MYLK(肌球蛋白轻链激酶)或其突变体. The present invention relates to novel compounds of formula (I), ...
“circle”) of heterocyclic indicates that at least one ring structure is present in such acompound, while the prefix hetero- (from Greekheteros, meaning “other” or “different”) refers to the noncarbon atoms, orheteroatoms, in the ring. In their general structure, heterocycliccompounds...
These are cyclic compounds which contain carbon atoms connected to each other in a ring (homocyclic). When atoms other than carbon are also present then it is called heterocyclic. Examples of this type are as follows: They exhibit some properties similar to aliphatic compounds. ...
Step-by-Step Solution:1. Definition of Alicyclic Compounds: - Alicyclic compounds are a class of organic compounds that are cyclic in structure but do not contain aromatic rings. They are characterized by ha
Click Here to see full-size tableThe carbon atoms bonded to the carbonyl group of an aldehyde may be part of saturated or unsaturated alkyl groups, or they may be alicyclic, aromatic, or heterocyclic rings.Nomenclature of aldehydes There are two general ways of naming aldehydes. The first met...
For studying, first, start with basic understanding and concept learning of aromatic compounds like benzene. Then understand how pyridine is derived by making some changes in benzene. Move further to study in detail its resonating structures, 3D conformers, crystal structures. Then students may study...
Studies on the Reactions of Heterocyclic Compounds. XIII. Basicity of 1,6-Naphthyridine and Its N-Oxides: Correlation to Peracid Oxidation Selective protonation of 1, 6-naphthyridine and its N-oxides was studied from the results of ultraviolet spectra in various concentrations of sulfuric acid......
Examples of Aromatic Compounds Aromatic molecules can be both homocyclic and heterocyclic. Heterocyclic molecules have atoms other than carbon in their molecular structure (eg., furan)[1]. Huckel’sRuleforAromaticCompounds Antiaromatic Compounds
The nucleobases can be grouped into two major forms:purinesandpyrimidines. While both purines and pyrimidines are heterocyclic aromatic compounds, they can be differed from each other based on the chemical structure. The purines occur as two carbon rings whereas the pyrimidines occur as one carb...
anduracilinstead ofthymine. The difference between uracil andthymineis the presence of methyl in thymine. While both purines and pyrimidines are heterocyclic aromatic compounds, they can be differed from each other based on the chemical structure. A purine hastwocarbon rings whereas a pyrimidine has...