Proteins are one of the most essentialbiomolecules. They serve as structural material, asenzymes, as transporters, as antibodies, or as gene expression regulators. They are made up ofpolymers comprised ofamino acids. They may be classified based on its form and main functions:globular proteins(sph...
Examples of structure formation within one molecule are polypeptides, globular proteins, DNA and collagen. The above represent thermodynamic phase transition phenomena and are amenable to the methods of statistical mechanics; they are not examples of dissipative structures. An interesting aspect of some ...
Inside the cell wall is the cell membrane, which is composed of a phospholipid bilayer with globular proteins. The cytoplasm has a membrane-less nucleus and some ribosomes. The genetic material in bacteria is mostly DNA which is not associated with histone proteins. Extrachromosomal DNA is also ...
The program was tested on predicting the accessible surface area of globular proteins, scoring proteins according to similarity to native, predicting protein disorder, and has performed remarkably well. In this paper we describe the program and its use. Specifically, we give as an example the ...
Valineis an aliphatic, non-polar, non-aromatic, branched chain, glycogenic, essential, and alpha (α-) amino acid that is not synthesized by the human body. It is extremely hydrophobic in nature and generally found inside globular proteins. It helps in the determination of the 3-D structure...
An example of this integration of pathways is that the amino acids alanine and glutamine, in addition to serving as the building blocks of proteins, can also enter gluconeogenesis. For this to happen, they need to shed their nitrogen, which is handled by enzymes calledtransaminases. ...
Class IV bacteriocins are complex types of bacteriocins that require large complexes of proteins with other macromolecules and non-proteinaceous moieties for activity. This class has not been studied much yet at the biochemical level. What are Lantibiotics?
Allosteric enzymes are proteins that have a second binding site for another molecule. In this second binding site, the protein can either bind to the substrate and change its shape or bind to a product, which causes the enzyme to change shape. Allosteric en...
(G) or partially degraded high G) can form more compact complexes with DNA than linear polymers. Amino-terminated PAMAM dendrimers also exhibit lower toxicity than more flexible amino-functionalized linear polymers. This is attributed to the lower adherence of ...
All proteins were extensively dialyzed against the same buffer (50 mM sodium phosphate, 5 mM MgCl2, pH 7.0) to exactly match buffer composition. Before being examined in the calorimeter, all samples were degassed for 10 min at a temperature close to the titration temperature (25 °C) to ...