Since the discovery of the first cephalosporin in 1945, medicinal chemists have been tinkering with its structure in order to change its properties. Medicinal chemists do this to antibiotics to see if they can make them more effective against different bacterial species or have fewer side effects....
More susceptible to antibioticsMore resistant to antibiotics Figure 5: Schematic diagrams of Gram-positive and Gram-Negative Cell walls. Image Credit:Kalina R. Atanasova. 6. Cell membrane Thecell membraneis a selectively permeable membrane of the bacteria made up of a phospholipid bilayer. It is ...
Mustard gas, or bis(β-chloroethyl) sulfide, (ClCH2CH2)2S, is a potentchemical warfareagent, whereas other sulfur compounds such as sulfanilamide (a sulfa drug),penicillin, andcephalosporinare valuedantibiotics.Syntheticorganosulfur compounds includepolysulfones, inertpolymersused in astronauts’ transparen...
with different components in various geographical countries. This research investigated the components of carbapenem resistanceintramedullary abscessin Escherichia coli, Klebsiella pneumoniae and Enterobacter spp. done as a multicentre research (n = 10). All third-generation cephalosporin-resistant E. coli, ...
humans if not treated and managed on time and properly. For this reason, scientists manufactured chemotherapeutic agents, known as antibiotics which act against the bacterial agent causing the disease, eliminating it from the system by killing it. The mechanisms of elimination of the antibiotics vary...