Therapeutic drug monitoring is performed by LC/MS on a routine basis at St. Olav Hospital. Over 200 drugs are ana- lyzed for both identification and quantification using this technique. This is made practical by high-throughputanalysis and the use of carefully applied methodology.The method for...
A correct evaluation of the therapeutic index should always comprise a large series of items: all desired and not desired effects and properties should be considered together with the physicobiochemical mechanisms of the drugs at cell and membrane levels. 展开 关键词:...
(50.0 kg) 95 中试(50.0 kg) 1.2 Analysis of the Reference Listed Drug Product 分析参考列表药品 1.2.1 Clinical 临床 The Reference Listed Drug (RLD) is Brand Acetriptan Tablets, 20 mg, and was approved in the United States in 2000 (NDA 211168) for therapeutic relief of moderate to severe...
(50.0 kg) 95 中试(50.0 kg) 1.2 Analysis of the Reference Listed Drug Product 分析参考列表药品 1.2.1 Clinical 临床 The Reference Listed Drug (RLD) is Brand Acetriptan Tablets, 20 mg, and was approved in the United States in 2000 (NDA 211168) for therapeutic relief of moderate to severe...
A reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management. Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) with strong analgesic activity. The analgesic efficacy of ketorolac has been extensively evaluat... JC Gillis,RN Brogden - 《Drugs》 ...
aTargeted drug delivery, also known as targeted medicine transshipment systems (TDDS), refers to the specificity of therapeutic drugs body needed to play a role in the direction of target area and have no or almost no effect on non-target tissue preparation, is a kind of new technology of ...
offered "a glimpse into the known effects of the gut microbiota on xenobiotic metabolism, with emphasis on cases where microbiome variations lead to different therapeutic outcomes"[17]. They discussed a few examples representing how the microbiome interacts with human metabolic enzymes in the liver ...
Based on the promising results obtained in recent basket trials, a multigene approach for all tumors might lead to new therapeutic options. Molecular pathology laboratories should 5402 submit your manuscript | www.dovepress.com Dovepress OncoTargets and Therapy 2016:9 Powered by TCPDF (www.tcpdf....
AIM To investigate the efficacy of switching to pegylated interferon-α-2a(Peg IFNα-2a) treatment in nucleos(t)ide analog(NA)-treated chronic hepatitis B(... LT He,XG Ye,XY Zho,... - 《World Journal of Gastroenterology》 被引量: 7发表: 2016年 Therapeutic effects of treatment with com...
Chronic myeloid leukemia (CML) is an uncommon leukemia but one that has been on the cutting edge of therapeutic and diagnostic discovery over the last three decades. With the identification of a cytogenetic abnormality half-century ago, then a gene rearrangement, and ultimately an abnormal tyrosine...