Using the ActiveModel for human prion protein, give an example of how significant change in secondary structure affects protein folding. Can a change in protein folding lead to disease? Find another example of a disease caused by a mutation in a...
New cases of FBS have been recently reported in the Middle and Far East in collaboration with specialized centers. Two novel mutations have been discovered in two unrelated Egyptian families. The first was two bases deletion, guanine and adenine, (c.253_254delGA) causing a frameshift mutation (...
bacteriophage therapy; bioinformatics-based design; structural analyses of phages; antibiotic resistance; mastitis; biofilm; milk model1. Introduction Mastitis is an intramammary inflammation, and is the most common and the most expensive disease concerning dairy animals worldwide [1]. The disease ...
(PADs), of which five isoforms have been identified. Hypercitrullination, as a result of increased PAD expression or activity, is associated with autoimmune diseases e.g., rheumatoid arthritis, lupus, Alzheimer’s disease, ulcerative colitis, multiple sclerosis, and certain cancers. Three common ...