Pre-treatment of exacerbation-derived CD8. + T cells with IL-12 significantly restored suppressive capability of these cells through upregulation of granzyme B. Our studies uncover immune-suppressive mechanisms of CNS-specific CD8. + Tregs, and may contribute to design of novel immune therapies for...
Safety and efficacy of siponimod (BAF312) in patients with relapsing-remitting multiple sclerosis JAMA Neurol (2016) There are more references available in the full text version of this article. Cited by (8) The Benefits and Risks of Switching from Fingolimod to Siponimod for the Treatment of ...
properly cited.Te f i rst treatment for multiple sclerosis exacerbation is usually short-term intravenous methylprednisolone (IVMP), with orwithout a regimen of oral prednisone taper (OPT). Tis study aims to evaluate the ef f ects of IVMP and OPTin comparison withIVMP alone in raising the risk...
Emotional stress and coping in multiple sclerosis (MS) exacerbations. Ninety-five pairs of MS patients in exacerbation and remission were compared on emotional stress in the previous three months. Patients in exacerbation sco... S Warren,KG Warren,R Cockerill - 《Journal of Psychosomatic Research》...
Treatment of acute exacerbation of multiple sclerosis with intravenous methylprednisolone Four patients suffered acute dystonic reactions caused by tetrabenazine. Because dystonic reactions have previously been reported only after dopamine receptor blockade and not with dopamine depletion, it is likely that the...
The fourth criterion was adopted because treatment from multiple clinics might overlap, making it difficult to determine the association between HIRA grade and asthma exacerbation. Similarly, 15,931 patients with asthma (6019, 6418, and 7257 patients from the first, second, and third periods, ...
to be responsible for the hypotonicity-induced ATP release from mouse astrocytes36. However, the treatment of cells with 50 mM GdCl3, an inhibitor of max-ion channels, did not suppress the CORT-induced enhancement in ATP release (P ¼ 0.989). Although no significant effects were observed ...
In previous studies we and others have demonstrated an association with apolipoprotein (APOE) ε4 genotype and the presence of cognitive deficits in multiple sclerosis (MS). In this follow-up study, we have assessed whether APOE ε4 status exacerbates progression of cognitive deficits in MS.: A...
METHOD OF TREATMENT OF PATIENT WITH CEREBROSPINAL SCLEROSIS FIELD: medicine, neurology. SUBSTANCE: in exacerbation period patient is subjected for plasmapheresis and additional cryoplasma sorption is carried out als... IR Shmidt,IV Krejnes,VS Sajapin,... 被引量: 0发表: 2000年 Plasmapheresis in m...
Fig. 4. The change in the serum Ang-2 levels at the point of acute exacerbation and during treatment in the AE-IIP patients who survived for 30 days (survivors) (a) and those who did not (non-survivors) (b). 4. Discussion This is the first study to report the possibility that Ang...