As a third mechanism of introducing Factor XIIa into the patient, full length or modified versions of the gene for human Factor XII can be directly administered in vivo. The advantage is provision of a universal gene therapy for hemophilia A and B, rather than separate gene therapies involving...
In vivo and ex vivo gene therapy strategies to treat tumors using adenovirus gene transfer vectors. Cancer Chemother Pharmacol 1999; 43 Suppl: S90-S99In vivo and ex vivo gene therapy strategies to treat tumors using adenovirus gene transfer vectors[J] . Ronald G. Crystal.Cancer Chemotherapy and...
A continuous source of Factor XIIa, as provided by a gene therapy, is therapeutic for both Hemophilia A and B. There are three ways to provide for gene therapy. In each case, the gene for Factor XII (or Factor XIIa) can be introduced into the cell by the usual means, including, but...
Ex vivo and in vivo adenovirus-mediated gene therapy strategies induce a systemic anti-tumor immune defence in the B16 melanoma model. 喜欢 0 阅读量: 26 作者:B Bonnekoh,DA Greenhalgh,SH Chen,A Block,DR Roop 摘要: The Journal of Investigative Dermatology publishes basic and clinical research ...
(Table4). These results are consistent with the sequencing data obtained in E3.5 embryos (Fig.2b), supporting the notion that gene editing efficiency is rAAV dose dependent. Table 4 Ex vivo gene editing after transduction of C57BL/6NJ zygotes with CRISPR-Cas9 rAAV vectors ...
Gene Therapy for Restenosis Ex vivo gene therapy with E2F-decoy succeeded in reducing graft occlusion rate after surgical bypass in a randomised, double-blind clinical trial. In the... Juha,Rutanen,Johanna,... - 《Drugs》 被引量: 6发表: 2002年 加载更多来源...
22 Different ex Vivo and Direct in Vivo DNA Administration Strategies for Growth Hormone Gene Therapy in Dwarf Animals Cibele Nunes Peroni, Nélio Alessandro de Jesus Oliveira, Claudia Regina Cecchi, Eliza Higuti and Paolo Bartolini Biotechnology Department, National Nuclear Energy Commission (IPEN-CN...
Until recently, progress in ex vivo gene therapy (GT) for human immunodeficiency virus-1 (HIV-1) treatment has been incremental. Long-term HIV-1 remission in a patient who received a heterologous stem cell transplant for acquired immunodeficiency syndrome-related lymphoma from a CCR5(-/-) donor...
Ex vivo gene therapy using targeted engraftment of NGF-expressing human NT2N neurons attenuates cognitive deficits following traumatic brain injury in mice. 来自 NCBI 喜欢 0 阅读量: 71 作者: L Longhi,DJ Watson,KE Saatman,HJ Thompson,C Zhang,S Fujimoto,N Royo,D Castelbuono,R Raghupathi,JQ ...
Until recently, progress in ex vivo gene therapy (GT) for human immunodeficiency virus-1 (HIV-1) treatment has been incremental. Long-term HIV-1 remission in a patient who received a heterologous stem cell transplant for acquired immunodeficiency syndrome-related lymphoma from a CCR5−/– donor...