Round cell sarcomaSarkome der Ewing-Familie sind aggressive Tumoren, die im Knochen und Weichgewebe zumeist bei Kindern und jungen Erwachsenen auftreten. Pathognomonisch f眉r klassische Ewing-Sarkome sind Fusionen zwischen einem Gen der RNA-bindenden TET -Familie ( EWSR1 oder FUS ) mit ...
Here, we present the first case of an undetected, local, very advanced extramedullary Ewing-like sarcoma of the medi- astinum. The clarification of the cause of death naturally has an effect on the cause of death statistics. On the other hand, it is often important for relatives to clarify...
A differential diagnosis is even harder to make with adamantinoma-like Ewing's sarcoma. This is a rare type of Ewing's sarcoma that, other than showing neuro-ectodermal differentiation, shows morphological, ultrastructural and/or immunohistochemical characteristics of epithelial tumours. It is essential...
(2006) Insulin-like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcoma. Int J Cancer, 119, 1039- 46.Benini S, Zuntini M, Manara MC, et al. Insulin-like growth factor binding protein 3as an anticancer molecule in Ewing's sarcoma. Int J Cancer. 2006;119:1039...
Picropodophyllin inhibits the growth of Ewing's sarcoma cells through the insulin?like growth factor?1 receptor/Akt signaling pathway. Ewing's sarcoma (ES) is the second most common type of pediatric bone tumor, and is associated with a poor prognosis. Picropodophyllin (PPP), a novel selec...
Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in ewing sarcoma cells. Int J Cancer 2016;138:497-506.Synergistic induction of apoptosis by a polo‐like kinase 1 inhibitor and microtubule‐interfering drugs in E wing sarcoma cells[J] . Lilly...
Ewing Sarcoma (ES) is mainly diagnosed during the second decade of life. It often compromises the appendicular skeleton but also can affect other bones. A surgical procedure is necessary despite its good response to chemotherapeutics and radiotherapy. When planning limb-sparing procedures for the youn...
We review the diagnostic categories that have emerged from the former wastebasket "undifferentiated round cell sarcoma" ("Ewing-like" sarcomas), with an emphasis on algorithmic exclusion of nonsarcomatous entities, diagnostic stratification of well-defined entities (Ewing sarcoma, rhabdomyosarcomas, ...
adamantinoma-like Ewing sarcomaEWSR1FLI1salivary glandAdamantinoma-like Ewing sarcoma (ALES) is a rare tumor that demonstrates the EWSR1 - FLI1 translocation characteristic of Ewing sarcoma despite overt epithelial differentiation including diffuse expression of cytokeratins and p40. Most cases of ALES...
ALES (adamantinoma-like Ewing sarcoma) is a rare subtype of Ewing sarcoma that is characterized by epithelial differentiation in addition to small round blue cells. Unlike typical Ewing sarcoma, ALES has been described in several cases in the head and neck. Herein, we describe a case of a 9...