Domains are the structural, functional and evolutionary units of proteins. They combine to form multidomain proteins. The evolutionary history of this molecular combinatorics has been studied with phylogenomic methods. Here, we construct networks of domain organization and explore their evolution. A time...
Asparagales, the largest monocot order, is renowned for its ecological, economic, and medicinal significance. Here, we leverage transcriptome data from 455 Asparagales species to explore the phylogeny of Asparagales. Moreover, we investigate the evolutionary patterns of the genes involved in allium flav...
Rosenberg & Grafton, Citation2012), to the observation of rapid movements at minuscule atomic levels used to synchronize and enable modern technology, such as GNSS. However, given its physical ubiquity, time has always structured our lives across many different scales and we have organized our ...
The evolution of biogeochemistry, retraces the important historical steps in part, covered by Gorham (Biogeochemistry 13:199–239, 1991) in the 18–19th centuries—with new emergent linkages and trends in 20–21st centuries. In the post-phlogiston period, key synthetic connections are made between...
PERSPECTIVES TIMELINE From empiricism to rational design: a personal perspective of the evolution of vaccine development Ennio De Gregorio and Rino Rappuoli Abstract | Vaccination, which is the most effective medical intervention that has ever been introduced, originated from the observation that ...
Aimed to address CP assemblies having as many turns as possible for their MD study, we tried to model a VLP helical arrangement large enough to analyze interactions and structures at atomic detail but not so large that the MD calculations would render unfeasible. After some exploratory work we ...
When two helium nuclei each of mass 4 atomic units (4He) are jammed together, it might be expected that they would form a nucleus ofberylliumof mass 8 atomic units (8Be). In symbols,4He +4He →8Be.Actually, however,8Be is unstable and breaks down into two helium nuclei. If the temp...
The resulting neutron star will have a density in the range of 1014–1015 grams per cubic cm, comparable to the density within atomic nuclei. The behaviour of large masses having nuclear densities is not yet sufficiently understood to be able to set a limit on the maximum size of a neutron...
of a loop prototype in ArchDB. The loop is defined by the bracing secondary structures of the loop, the number of residues forming the aperiodic structure, its conformation (ϕ and ψ backbone dihedral angles of the participating residues), and the geometry of the loop. The atomic model of...
It remains contentious whether the meteoritic material delivered to the terrestrial planets after the end of core formation was rich or poor in water and other volatiles. As Venus’s atmosphere has probably experienced less volatile recycling over its hi