how it should be integrated into a clinical decision." The components of EBM can be illustrated by a Venn diagram2, (Figure 1), where at the intersection of (a) clinical judgement (based on clinical experience and prior knowledge), (b) patients' values and preferences (based on patient ex...
Progressive change in body composition occurs with ageing, characterised by four phenotypes in older adults, that can increase the likelihood of mortality through comorbid disease [11]: sarcopenia, healthy weight, obesity and sarcopenic obesity [12] (Fig.1). Fig. 1: Venn diagram exploring the fou...
Based on TMAO’s detrimental association with kidney damage of diverse aetiologies19,20similar to renal fibrosis46, we investigated the impact of TMAO on human primary renal fibroblasts (HRFs). In HRFs, unlike platelets47, TMAO stimulation resulted in rapid [Ca2+]iincrease (Fig.5A). In endothe...
Additional Contributions: We gratefully acknowledge the following individuals for their contributions to this project, including AHRQ staff (Justin Mills, MD, MPH, and Tracy Wolff, MD, MPH) and RTI International–University of North Carolina–Chapel Hill Evidence-based Practice Center (EPC) staff (Ca...
In Norway, clearcutting is the common management practice although forest owners have relatively greater freedom to manage their forests according to their own objectives within the legal framework [19]. In European Russia, most final fellings are clearcuts and uneven-aged forestry with selective ...
Internalizing disorders encompass anxiety, fear and depressive disorders, which exhibit overlap at both conceptual and symptom levels. Given that a neurobiological evaluation is lacking, we conducted a Seed-based D-Mapping comparative meta-analysis inclu
(A–C) Venn diagram of the action targets of WGP and the targets of aging (A), atherosclerosis (B), and fatigue (C). (D–F) Protein-protein interaction network reflected in cytohubba-MCC identified hub genes in the gene lists for WGP-aging (D), WGP-atherosclerosis (E), and WGP-...
Figure 1. Venn diagram of behavioral (repellence, attraction and dispersal, and aggregation) and electrophysiological (electroantennogram (EAG)) responses, and no responses, of females to conspecific-produced sex pheromones. These complications have occurred with sufficient frequency to cause the adop...
The top five biological processes, cellular responses, and molecular functions are illustrated in Figure 4 based on the counts. Figure 4. A bubble plot displaying the five most enriched GO, BP, CC, and MF terms of the top 10 hub genes identified by CytoHubba. GO, Gene Ontology; BP, ...