REAL-TIME PROCESSING OF ELECTROPHYSIOLOGICAL EVENTS AT THE NEUROMUSCULAR JUNCTIONA parameter of considerable interest in synaptic physiology is the average number of quanta of neurotransmitter (Acetylcholine, ACH) released from the pre-synaptic nerve terminal. The results of such quantal analysis have ...
Neuromuscular Junction (NMJ): Postsynaptic Events in Neuromuscular TransmissionAt vertebrate neuromuscular junctions the postsynaptic response to the nerve is determined primarily by two ion channel species and the geometry of the postsynaptic region. Acetylcholine receptors mediate the influx of excitatory ...
(RBPs) in neuromuscular biology and on their therapeutic potential for various neuromuscular disorders, we became interested several years ago in examining the impact of Staufen1 in skeletal muscle development, at the mature neuromuscular junction, as well as in Myotonic Dystrophy Type I (DM1)22–...
Frank, E., andG. D. Fischbach . 1979. Earlyevents in neuromuscular junction formation in vitro . J. Cell Biol. 83:143-158 .FRANK, E. & FISCHBACH, G. D. (1979). Early events in neuromuscular junction formation in-vitro. Induction of acetylcholine receptor clusters in the postsynaptic ...
The three main cellular components of the neuromuscular junction (NMJ) are affected by a single local injection of botulinum neurotoxin (BoNT). Motor nerve terminals are known to synthesize and release acetylcholine (ACh) spontaneously, or in response to nerve stimuli. The main action of BoNTs ...