Mathematical models to quantify the influence of these parameters, individually and/or jointly, on liposome partitioning in ATPS were developed. The models were statistically tested and verified by experimentation. This approach was then used to define the conditions for the preferential accumulation...
The concentration of propylene glycol and methylparaben was kept constant at 15% and 0.3%. The hydrogel formulation was evaluated for various physicochemical parameters like percentage drug content, spreadability, and drug release. Formulation H9 was the highest drug content, 98.23 ± 0.031%, and the...
Effect of different rivastigmine formulations administered through different routes of administration in scopolamine induced amnesia on parameters of passive avoidance task. (A) AT (acquisition time), LT (latency time to enter into darker compartment), D (time spent in the darker compartment), L (ti...
The viscoelastic parameters of synovial fluids (SF) from various joint diseases and pure hyaluronic acid (HA) solutions of various concentrations were inve... I, Anadere,H, Chmiel,W, Laschner - 《Biorheology》 被引量: 53发表: 1979年 Bacterial Polysaccharides: Production and Applications in Cosme...
Table 3 Pharmacokinetic parameters for intravenous administered free PTX, PTX-NCs, Lipid/PTX-NCs, and Cmab/Lipid/PTX-NCs. Full size table The study was also conducted to determine the effect of surface-modified nanocrystals on organ distribution (Fig. 6). Free PTX gets distributed to all the...
Pharmacokinetic parameters of dehydrosilymarin suspension and dehydrosilymarin-loaded liposomal suspension (n=3, 80 mg/kg). Data expressed as mean±SD. P arameter s Un it Dehydrosilymarin Dehydrosilymarin-loaded proliposomes AUCt t1/2 tmax MRT μg·mL–1·h h h h 5.58±0.21 20.63±5.03 2.00...
It was shown that the nanoliposome encapsulation of GTE improved its beneficial properties including antioxidant activities. Variations in GTE concentration as well as type of capsulation were critical in some of the parameters studied, i.e. pH, acidity, ascorbic acid and anthocyanins content. Higher...
Significant differences in the pharmacokinetic parameters of PLD were observed between the PFD injec- tion and the PFD-loaded liposomal formulation. Liposomes provided a higher mean residence time (2.93-fold), clearance half-life (t1/2α; 2.13-fold), and distribution half-life (t1/2b; 3.42-...
of native structure and function.12 Numerous types of compartmentalized organic particles (for example, micelles, liposomes, polymersomes and so on) have successfully been used for the stable integration of multiple proteins.13,14 Although the insertion of functional proteins into a variety of ...
In vivo Biophysical Characterization of Skin Physiological Differences in Races The role of race in modulating skin responses has been investigated. Several parameters (skin thickness, transepidermal water loss, water content of the st... E Berardesca,J De Rigal,JL Leveque,... - 《Dermatologica》...