水杨酸盐、双香豆素、大剂量速尿(250mg)、安妥明等可取代左甲状腺素与血浆蛋白结合,从而导致fT4水平升高。 奥利司他: 当奥利司他与左甲状腺素同时服用时,可能发生甲状腺功能减退和/或甲状腺功能减退控制不佳。这可能是由于碘盐和/或左甲状腺素的吸收减少。 司维拉姆: 司维拉姆可降低左甲状腺素的吸收。因此,推荐在联...
(e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T3 and T4 levels change, TSH levels remain normal, and patients are clinically euthyroid. Actions of particular betaadrenergic antagonists may be impaired when a hypothyroid patient is conve...
Info: for product conversion purposes, 100 mcg levothyroxine = 25 mcg liothyronine = 60-65 mg thyroid (porcine) = 1 grain liotrix hypothyroidism [50-200 mcg PO qd] Start: 1.6 mcg/kg/dose PO qd, then adjust dose by 12.5-25 mcg/day q4-6wk; Info: adjust dose based on TFTs; doses...