Melting pot of tick-borne zoonoses: the European hedgehog contributes to the maintenance of various tick-borne diseases in natural cycles urban and suburban areas. Parasit. Vectors 10, 134. http://dx.doi.org/10.1186/s13071-017-2065-0.
Red foxesand owls, hawks, and other birds of prey eat European wildcats. Their lifespan can end early due to predators. The European wildcat is generally rare, although it is more abundant in certain areas than others, and it is a protected species. The main threat to the species is cro...
Pathway enrichment analysis reveals that in our family cohort, age-associated DNA methylation sites are densely packed around genes working in pathways such as the hedgehog signaling pathway, the MODY pathway, and T1D pathway (Additional files8and10). These findings suggest intriguing connections betwe...
24]. It is therefore thought to depend on reservoir hosts to complete its life-cycle. The white-footed mouse (Peromyscus leucopus) is probably the main reservoir for human infection in the USA [25,26], whereas the situation is less clear for Europe. Several species including wild ruminants, ...
(1998). Genetic differentiation among local populations of the European hedgehog (Erinaceus europaeus) in mosaic habitats. Mol Ecol 7: 1599–1604. Article CAS PubMed Google Scholar Beerli P . (2006). Comparison of Bayesian and maximum-likelihood inference of population genetic parameters. ...
An example is the paediatric development of the sonic hedgehog inhibitor glasdegib, which was waived due to concern for skeletal toxicity as a class-effect [72]. At the same time, it was considered important to see the high number of agreed PIPs in context of the known high failure rate ...
Cyclosporine promotes gingival fibroblast proliferation via the TGF-β and Sonic hedgehog (Shh) pathways [53]. According to a substantial body of research, TGF-β1 has a powerful inhibitory impact on hepatocytes proliferation either in vivo or in vitro study as well as in normal, regenerative, ...
SAG treatment stimulates Sonic hedgehog (Shh) signaling, and, thereby the accumulation of Smoothened (SMO) in the cilium [38]. Cilia and SMO were visualized using antibody labeling (Fig. 3a, b). We recorded two confocal image stacks per condition (control and SAG treatment), and submitted ...
Hedgehogs from a captive population in the federal state of Baden-Württemberg and from hedgehog caretaking sta- tions in various areas of Germany were bled from the saphenous vein or died naturally. None of the hedgehogs were sacrificed for this study. For Germany, permission to trap rodents...
However, there is basically no specific signaling pathway in the process of anti-tumor immunity, such as Notch signaling pathway; PI3K–AKT signaling pathway; hedgehog signaling pathway; NF-κB signaling pathway; JAK–STAT signaling pathway; Wnt/β-catenin signaling pathway, etc [17,36,37,38,39...