In this Cell Science at a Glance article and the accompanying poster, we summarise the current knowledge on eukaryotic ribosome biogenesis, with an emphasis on the yeast model system. 展开 关键词: SMALL NUCLEOLAR RNAS POLYMERASE-I TRANSCRIPTION NUCLEAR EXPORT SACCHAROMYCES-CEREVISIAE PRE-RIBOSOMES ...
The presence in green algae and plants of elongation enzymes able to use the bacterial specific metabolite ADP-glucose through enzymes related to prokaryotic glycogen synthase are at first glance in line with this hypothesis. GlgA2, a cyanobacterial glycogen synthase, was initially thought to ...
Although the RP genes are not homologs of the RP mRNAs identified in this study, our findings nevertheless support the hy- pothesis that regulation of ribosome biogenesis is a deeply conserved function of Sm proteins. Sequence covariation is generally considered a hallmark of conserved base-pairing...
A quick glance at Figure3shows that the read depth over intronic sequences is very low. Meta-gene analysis of bothDrosophilaand human Sm-associated intron-containing mRNAs showed that the vast majority of reads map to exons, and the IPs did not pull down more pre-mRNAs than the controls di...
Originally Lipid droplets (LDs) were considered as being droplets for lipid storage only. Increasing evidence, however, demonstrates that LDs fulfill a ple