Over-expression of ERT(ESX/ESE-1/ELF3), an ets-related transcription factor, induces endogenous TGF-β type II receptor expression and restores the TGF-β signaling pathway in Hs578t human breast cancer cells. Jay Chang,Cecile Lee,Ki-Baik Hahm,Youngsuk Yi,Shin-Geon Choi,Seong-Jin Kim. ...
Mutual repression of transcriptional activation between the ETS-related factor ERG and estrogen receptor.doi:10.1038/sj.onc.1207094Transcription factors are known to interact with each other to modulate their transcriptional activity. In this study, we found that the transcriptional activity of human Erg...
We report here the isolation ofTel-2, a novel member of the Ets transcription factor family, with high homology to Tel/ETV-6. Tel-2 is the second mammalian member of the Tel Ets family subclass whose prototype Tel is involved in various chromosomal translocations in human cancers. Six ...
ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor 1994, Nature The Ets family of transcription factors 1993, European Journal of Biochemistry Functional ecdysone receptor is the product of EcR and Ultraspiracle genes 1993, NatureView...
Choroidal neovascularization (CNV) is the basic feature of neovascular age-related macular degeneration (AMD), the leading cause of blindness in elders. Macrophages and microglia promote CNV via producing pro-angiogenic factors and inflammatory cytokines. Transcription factor E26 transformation specific-1 ...
Transcription FactorBreast CancerPEA3The ets genes encode eukaryotic transcription factors that are involved in tumorigenesis and developmental processes. The signature of the Ets family is the ETS-domain, which binds to sites containing a central 5,-GGAA/T-3, motif. They can be sub-classified ...
CoAA (Coactivator Activator) increases the activity of the ETS-related transcription factor ERM by modulating its sumoylationVerreman, KBaert, J LDrobecq, HDe Launoit, YMonte, D
The present invention relates to a nucleic acid capable of controlling the expression of a heterologous gene and of being selectively activated by an Ets-transcription factor related compound. The invention further relates to constructs, host cells comprising said nucleic acid, methods for recombinant ...
Cloning An Ets-Related Transcription Factor Involved In A Novel Epigenetic Mechanism Of Mammary Carcinogenesis
Janknecht R, Monte D, Baert JL, de Launoit Y (1996) The ETS- related transcription factor ERM is a nuclear target of signaling cascades involving MAPK and PKA. Oncogene 13:1745-1754Janknecht,...