gene transcriptionThe human telomerase gene (hTERT) is repressed in most somatic cells. How transcription factors activate the hTERT promoter in its repressive chromatin environment is unknown. Here, we report that the ETS family protein ETS variant transcription factor 5 (ETV5) mediates epidermal ...
别名ETS-domain transcription factor; FEV; FEV_HUMAN; Fifth Ewing variant protein; mPet1; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1; Protein FEV. 抗体的鉴定: 1)抗体的效价鉴定:鉴定效价的方法很多,包括有试管凝集反应,琼脂扩散试验,酶联免疫吸附试验等。常用的抗原...
Results of previous studies suggested that the barrier is deficient in ets variant 5 (ETV5) gene-deleted mice; therefore, microarray data were examined for changes in tight junction-associated genes. The tight junctional protein claudin 5 (CLDN5) was decreased in testes of 8-day-old Etv5(-...
Expression of the novel gene embryo implantation factor 2 (EMO2) in the mouse uterus at the implantation sites Objective: The aim of this study was to identify a novel implantation-related molecule and to examine EMO2 expression in the mouse uterus during the peri-i... Z Sun - ELSEVIER ...
Here, we report that the expression of Pea3 and Erm (or Etv5, Ets variant gene 5), which encode Pea3 subfamily ETS domain transcription factors, is initially restricted to the distal buds of the developing mouse lung. Erm is transcribed exclusively in the epithelium, while Pea3 is ...
[19] Cheng X,Jin Z,Ji X,et al.ETS variant 5 promotes colorectal cancer angiogenesis by targeting platelet- derived growth factor BB[J].International Journal of Cancer,2019,145(1):179-191. [20] Gallant S,Gilkeson G.ETS transcription factors and regulation of immunity[J].Archivum ...
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Recurrent mutations are frequently associated with transcription factor (TF) binding sites (TFBS) in melanoma, but the mechanism driving mutagenesis at TFBS is unclear. Here, we use a method called CPD-seq to map the distribution of UV-induced cyclobutan
DNA描述 Homo sapiens ETS proto-oncogene 1, transcription factor (ETS1), transcript variant 1, mRNA DNA大小: 5139 bp DNA编码区: atgagctactttgtggattctgctgggagcagccccgtcccttactcagcgcctcgtcct gcagtggtgaggcaaggacctagcaacacttatgaagatcctcgaatgaactgtggtttc cagtccaattatcaccagcaaagaccttgctaccccttttgggat...
variant translocations have been described that fuse EWS to other ETS family transcription factors, such as t(21;22) and EWS/ERG fusion. While the exact role of the fusion proteins remains unknown, they are felt to act primarily as aberrant transcription factors that play an important role in...