Research methods: A questionnaire form was constructed, conducted in March 2023 among 59 students studying majors assigned to the sciences of culture and religion (socio-cultural animation with cultural education, information architecture, ethnology and cultural anthropology, information ...
Full size image REtr- and c-KIT(N822K)-expanded progenitor cells exhibit a phenotype similar to FAB AML-M2 myeloblastic cells After ex vivo expansion, REtr- and REtr+c-KIT(N822K)-expressing cells were analyzed via FACS for cellular differentiation markers. In agreement with the published data...
Full size image Moderate concentrations of ATO mainly promotes ETotic cell death in NB4 cells To better understand the mechanism behind ATO-induced cell death, we dual stained cells with lactadherin and PI (Fig. 2a). Apoptosis was analyzed by flow cytometry, and confirmed by frequency of cells...
Full size image Different mouse models have been used to investigate the function of AE. The knock-in of AE in the endogenous AML1 locus inhibited hematopoiesis, resulting in lethality.24, 25 A conditional AE knock-in approach resulted in enhanced replating capacity of myeloid progenitors without...
Download: Download full-size image Scheme 1: si-EzH1@HNP@S30 specifically deliver EzH1 siRNA in AML1-ETO cells through CD33 and exhibit an enhanced EzH1-specific RNAi mechanism to execute a superior anti-AML therapy and abrogate the C-Myb and EzH1 crosstalk in AML. ...