Matrix type tablets formed from microparticles coated with ethylcelluloseThe paper reports on formulation results of matrix tablets with controlled drug release using Methocel® K 4M CR and K 15M CR. Both auxiliary products in concentrations above 20% by weight ensured release of theophylline in ...
Uses Used as a binder and filler in dry vitamin preparations, as a component of protective coatings for vitamin and mineral tablets, and as a fixative in flavoring compounds. It is a cellulose ether containing ethyoxy groups attached by an ether linkage and containing an anhydrous basis of not...
5.1.5Ethyl cellulose Ethyl celluloseis a compound of cellulose derivatives in which some of the hydroxyl groups present in the repeated glucose units are converted to the ethyl ether group. Ethylene cellulose is structurally similar to cellulose and cellulose acetate, except that the ethoxy group (...
Ethylcellulose in Direct Compression Modified Release Tablets: Impact of Polymer Structure and Formulation VariablesSkinner, G.WHarcum, W.WDürig, TSkinner G., Harcum W., Durig T., Ethyl cellulose direct compression modified release tablets: Impact of polymer structure and for...
An extended release dosage composition of pharmaceutically active substances that have a water contact angle (θ) such that cos θ is between +0.9848 and −0.9848 presented as a matrix tablet containing the said pharmaceutically active substances, with
A sustained-release tablet formulation should ideally have a proper release profile insensitive to moderate changes in tablet hardness that is usually encountered in manufacturing. In this study, matrix aspirin (acetylsalicylic acid) tablets with ethylcellulose (EC), Eudragit RS100 (RS), and Eudragit...
ORIGINAL RESEARCH Synthesis and Characterization of a Cationic Thiomer Based on Ethyl Cellulose for Realization of Mucoadhesive Tablets and Nanoparticles Deni Rahmat & Clairine Devina Pages 2321-2334 | Published online: 20 May 2022 Cite this article CrossMark Full Article Figures & data References...
1. A controlled release formulation comprising a substrate containing an active agent in an amount sufficient to provide an effect in an environment of use, said substrate coated with an aqueous dispersion of plasticized ethylcellulose in an amount sufficient to obtain a controlled release of said ...
For solid compositions, conventional excipients include, for example, pharmaceutical grades of mannitol, lactose, starch, magnesium stearate, sodium saccharin, talc, cellulose, glucose, sucrose, magnesium carbonate, and the like. Liquid pharmacologically administrable compositions can, for example, be prep...
Fine-Particle ethylcellulose as a tablet binder in direct compression, immediate-release tablets. Drug Dev Ind Pharm. 2001;27:633-41.Desai, R.; Neau, S.; Pather, S.; Johnston, T., Fine-particle ethylcellulose as a tablet binder in direct compression, immediate-release tablets. Dru Dev....