Water Solubility: H2O: 80 g/L (20 ºC) Storage Conditions: On storage, it is slowly decomposed by water. Vapor Pressure: 112mmHg at 25°C Vapor Density: 3 (20 °C, vs air) Flammability characteristics: Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°...
Small sugar acetates are known to be extraordinarily CO 2-philic, but cellulose triacetate, a crystalline high molecule weight polymer is CO 2 insoluble. Therefore, an amorphous high molecular weight polymer with pendant sugar acetates was synthesized. This polymer, poly(1- O-(vinyloxy) ethyl-2...
1. A controlled release formulation comprising a substrate containing an active agent in an amount sufficient to provide an effect in an environment of use, said substrate coated with an aqueous dispersion of plasticized ethylcellulose in an amount sufficient to obtain a controlled release of said ...
It is well known that the crystalline form of the active pharmaceutical ingredient (API) of a particular drug is often an important determinant of the drug's ease of preparation, hygroscopicity, stability, solubility, storage stability, ease of formulation, rate of dissolution in gastrointestinal flu...
An antisolvent is a solvent in which the compound has low solubility. Suitable solvents for preparing crystals include polar and nonpolar solvents. Examples of solvents for crystallization include, for example, toluene, n-pentane, n-hexane, n-heptane, n-octane, n-decane, n-dodecane, diethyl ...
Solubility of Compound 1 at Room Temperature The solubility of Compound 1 was determined at room temperature in the various solvent and solvent mixtures indicated below in Table 2. TABLE 2 Solubility Solventmg/mL Acetone11 Acetone:H2O<8.9
Herein, the reaction was performed in heptane solution, which reduces the dispersion of the obtained product due to the dependence between the length of the oligomeric chain and its solubility in the reaction medium (Scheme 1) [55]. The longer chain of the oligomer reduced the solubility of ...