The objective of medical research is to seek scientific truths and support these ethical principles. The integrity of clinical investigation involves the just and honest conduct of experimentation, the honest analysis and reporting of data, and then, the fair peer review and publication of these ...
Reporting bias in clinical trials: Progress toward transparency and next steps. PLoS Med. 2022;19(1):e1003894. doi:10.1371/journal.pmed.1003894PubMedGoogle ScholarCrossref 20. Topol EJ. Welcoming new guidelines for AI clinical research. Nat Med. 2020;26(9):1318-1320. doi:...
This article is available as a PDF only. KA Nolan - 《Yale Journal of Biology & Medicine》 被引量: 796发表: 1982年 ETHICS AND CLINICAL RESEARCH. Discusses the ethical approach to human experimentation. Areas where experimentation in man takes place; Reasons for urgency of attention to the ...
Ethics, an essential dimension of human research, is considered both a discipline and practice. For clinical research, ethically justified criteria for the design, conduct and review of a clinical investigation can be identified by obligations to both the researcher and human subjects. Informed consent...
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia Druker B Talpaz M Resta D et al.See more New England Journal of Medicine 4625Citations 1094Readers Add to libraryView PDF What makes clinical research ethical? Emanuel E Wendler D Grady C ...
Ethics in Psychiatric Research An abstract is unavailable. This article is available as HTML full text and PDF. RM Salomon - 《Journal of Clinical Psychiatry》 被引量: 12发表: 1999年 Ethics in Psychiatric Research Controversy has arisen in recent years about the participation of psychiatric patient...
Export PDF Favorites Scan Get Citation Shared Abstract Figures/Tables References Cited by In the clinical trials, the rights and interests of participants must be considered. Ethical principles including the Declaration of Helsinki for clinical research have been established, and the institutional ...
fontselect.htinc" BEGIN BUTTONS // --> END BUTTONS #include virtual="/journals/button_includes/noscriptbuttons1.htinc" [Access article in PDF] Open Peer Commentaries _title Clarifying the Ethics of Clinical Research: A Path toward Avoiding the Therapeutic Misconception _/title _authorname Paul ...
In medical practice and research, there is often a wider range of uncertainty or professional disagreement than capacity to run clinical trials. Uncertainty alone is not sufficient to ensure that studies bridge a knowledge gap critical to advancing the ability of clinicians and health systems to prom...
Physicians engaged in clinical research must address the challenge to determine whether a potential new intervention represents an advance over current methods, whether the new intervention would avoid harms currently incurred, whether it would save lives currently lost. They face the dilemma between the...