In the monkeys which had received ethanol the metabolism of alcohol increased from 17.4 mg per 100 ml per hour to 26.6 mg and antipyrene half-life decreased from 61.0 minutes to 49.9 minutes. The carbohydrate animals showed no significant change in alcohol metabolism or antipyrene half life. ...
the main portion of the metabolism (>90%) occurs in the liver, where alcohol dehydrogenase reduces it to acetaldehyde.15 Although ethanol has some direct actions on the cardiovascular system, its main clinical action in acute intoxication is that of a central ...
Stimulants of ethanol metabolism, such as fructose, are not sufficiently effective, and use of analeptics is not recommended because of the possibility of precipitating convulsions.The immediate concern in the treatment of alcoholics is detoxification and management of the ethanol withdrawal syndrome. ...
Because recovery time is measured from the cessation of ethanol exposure, it may be affected by changes in ethanol metabolism. Adh mutants, as mentioned, have very small effects on ethanol-induced sedation, but they show large differences in internal ethanol concentrations from wild types upon ...
Interestingly, LDLR-related protein (LRP) is involved in various cellular processes such as lipid metabolism, cell migration, and endocytosis30. Particularly, LRP1 activation inhibits Aβ aggregation31,32 and down-regulates NF-κB-dependent proinflammatory cytokines33,34, which are critical for AD ...
Table 1 Interactional analysis with generalized linear model among ethanol, high-fat diet (HFD) and sex on neuroendocrine metabolism-related blood phenotypes in rat offspring. Full size table With respect to serum corticosterone levels (Table 1), when compared to normal diet, it was increased in ...
Next, we investigated whether MSH ameliorates ethanol-induced lipid accumulation in hepatic tissue through modulating fatty acid metabolism. First, hepatic and serum TG levels were assessed to elucidate the effect of MSH on the TG synthesis. We found that 14 days of ethanol administration significantly...
alcohol dehydrogenase and pyruvate decarboxylase, further comprises DNA encoding proteins which enable the host to transport and metabolize an oligosaccharide. The host expresses the DNA at a level such that the host produces ethanol as a primary fermentation product from the metabolism of the ...
15: 335-339 (1981) brain ethanol fetus leucine liver metabolism protein Effects of Acute Ethanol Exposure upon i n Vivo Leucine Uptake and Protein Synthesis in the Fetal Rat STANLEY E. FISHER."'" MARY A N N E BARNICLE. BECKY STEIS. IAN HOLZMAN. A N D DAVID H VAN THlEL Departments ...
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