To determine the therapeutic effects of two selective GABA-A agonists, zopiclone and eszopiclone, in the treatment of insomnia. METHODS: This study comprised a phase III, single-center, randomized, double-blind, double-dummy, parallel-group, non-inferiority trial. Patients were randomized to receive...
eszopiclone Medical Wikipedia Related to eszopiclone:Zaleplon,Lunesta,Ramelteon es·zo·pic·lone (ĕs′zō-pĭk′lōn) n. An oral sedative and hypnotic drug, C17H17ClN6O3, used to treat insomnia. [es-,isomer pref.; seeescitalopram+zopiclone,a sedative(perhaps(a)zo-+pi(perazine)+ (cy)cl...
Eszopiclone, the S-isomer of zopiclone, has been available in Europe since 1992 (Anon 2005a). It is a nonbenzodiazepine hypnotic agent of the cyclopyrrone class (sedative hypnotic class of drugs). Eszopiclone has a single chiral center with an (S)-configuration (Sepracor 2005) and is ...
Hypnotics including zolpidem, zopiclone, eszopiclone, zaleplon • Benzodiazepines: Rarely used secondary to dependency; shown to reduce REM sleep percentage10 • Trazodone • Mirtazapine • Caution in older adults with all sedating medications, which can increase risk of falls at night • Neuro...
(20.2%), quetiapine (12.3%), and clonazepam (11.1%). The approved drugs were used in 9.9% of the patients, especially eszopiclone (4.7%) and zopiclone (3.6%). Benzodiazepines and Z compounds predominated in the elderly and individuals with chronic insomnia.ConclusionsThe pharmacological treatment...