型号规格:本品为片剂,每片含有效成份1mg/2mg/3mg,每瓶100片装。 药品详情: 【艾司佐匹克隆eszopiclone 简述】 艾司佐匹克隆eszopiclone又名右佐匹克隆; 右旋佐匹克隆; 埃佐匹克隆; 艾司佐匹; 本品为环毗咯的吡咯吡嗪衍生物。 【艾司佐匹克隆eszopiclone 适应症】 艾司佐匹克隆可用于入睡困难,夜间维持睡眠困难...
While pharmacodynamic tolerance or adaptation to some adverse depressant effects of LUNESTA® may develop, patients using 3 mg LUNESTA® should be cautioned against driving or engaging in other hazardous activities or activities requiring complete mental alertness the day after use....
The synthesis of eszopicolone involves enzymatic resolution of a zopicolone derivative to give the chiral compound as depicted in the Scheme 12. Pyrazine-2,3- dicarboxylic acid anhydride was reacted with 2-amino- 5-chloropyridine (61) in refluxing acetonitrile to generate 3- (5-chloro-2-pyr...
(ClinicalTrials.gov registration number: NCT00612157).#Academic sleep disorder center.#160 adults (mean age, 45.7 years [SD, 7.3]; mean apnea-hypopnea index, 36.9 events/h [SD, 23]) with newly diagnosed obstructive sleep apnea initiating CPAP.#Eszopiclone, 3 mg (n = 76), or matching ...
Stage 2 sleep: increase (2–3 mg) Conclusions • Better PSG (to night 29) and patient-reported (to night 44) sleep • No tolerance or rebound insomnia • No detrimental effects on next day psychomotor performance • Significant improvements in sleep and daytime function in those switched...
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(i.e., less than formal psychomotor testing). While pharmacodynamic tolerance or adaptation to some adverse depressant effects of LUNESTA® may develop, patients using 3 mg LUNESTA® should be cautioned against driving or engaging in other hazardous activities or activities requiring complete ...
The usual dose to improve or maintain sleep in most adults is 2 or 3 mg before bedtime. Persons over the age of 65 years usually are treated with 1 or 2 mg. Eszopiclone should be taken immediately before going to bed since the onset of sedation may occur as rapidly as 10 minutes. It...
Initial dose: eszopiclone 1 mg orally, once a day immediately before bedtime.The dosage of eszopiclone may be increased to 2 mg or 3 mg if insomnia persists after 7 to 10 days of treatment, but doing this may increase the risk of sleepiness the next day. The maximum dose of eszopiclone ...
Do not drive after taking eszopiclone. You may still feel the effects of eszopiclone after you wake up in the morning, so do not drive or perform unsafe tasks until you are fully awake. The risk is greater with the 3mg dose. Do not take eszopiclone if you have drunk alcohol that evenin...