The usual dose to improve or maintain sleep in most adults is 2 or 3 mg before bedtime. Persons over the age of 65 years usually are treated with 1 or 2 mg. Eszopiclone should be taken immediately before going to bed since the onset of sedation may occur as rapidly as 10 minutes. It...
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CNS Depressant Effects and Next-Day Impairment LUNESTA® is a CNS depressant and can impair daytime function in some patients at the higher doses (2 mg or 3 mg), even when used as prescribed. Prescribers should monitor for excess depressant effects, but impairment can occur in the ...
Initial dose: eszopiclone 1 mg orally, once a day immediately before bedtime.The dosage of eszopiclone may be increased to 2 mg or 3 mg if insomnia persists after 7 to 10 days of treatment, but doing this may increase the risk of sleepiness the next day. The maximum dose of eszopiclone ...
Do not drive after taking eszopiclone. You may still feel the effects of eszopiclone after you wake up in the morning, so do not drive or perform unsafe tasks until you are fully awake. The risk is greater with the 3mg dose. Do not take eszopiclone if you have drunk alcohol that evenin...
2-fold higher Cmaxand 2-fold greater elimination half-life than the (R)-enantiomer.The two most frequent adverse events associated with eszopiclone treatment are unpleasant taste and headache. Other less frequent side effects include somnolence, dry mouth, and nausea. ...
LUNESTA is a CNS depressant and can impair daytime function in some patients at the higher doses (2 mg or 3 mg), even when used as prescribed. Prescribers should monitor for excess depressant effects, but impairment can occur in the absence of symptoms (or even with subjective improvement)...
(ClinicalTrials.gov registration number: NCT00612157).#Academic sleep disorder center.#160 adults (mean age, 45.7 years [SD, 7.3]; mean apnea-hypopnea index, 36.9 events/h [SD, 23]) with newly diagnosed obstructive sleep apnea initiating CPAP.#Eszopiclone, 3 mg (n = 76), or matching ...
Stage 2 sleep: increase (2–3 mg) Conclusions • Better PSG (to night 29) and patient-reported (to night 44) sleep • No tolerance or rebound insomnia • No detrimental effects on next day psychomotor performance • Significant improvements in sleep and daytime function in those switched...
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