and the scalp hair is usually more permanent. Thevoice boxis smaller and the vocal cords shorter, giving a higher-pitched voice than in males. In addition, estrogens suppress the activity of sebaceous (oil-producing) glands and thereby reduce the likelihood ofacnein the female. In experimental...
Estradiol in men is quintessential in many sexual physiological processes.#To evaluate the effect of Estrogen levels on infertile men and their semen parameters#In this prospective case-control hospital based study, a total number of 50 infertile men with primary and secondary infertility (case group...
Further, some preliminary results suggest that in a clinical setting, short-term E2 treatment is able to reduce plasma levels of Aβ in post-menopausal women naïve to HT [20], although the significance of plasma Aβ in terms of both AD pathogenesis and diagnostic value remains controversial...
Blood estrogen levels also rise slightly in males before and during puberty. The source of these estrogens is probably the Sertoli cells of the testes (see Chapter 4). The presence of estrogens in males near puberty explains why some pubertal males exhibit slight growth of the mammary glands ...
multiple comparisons test; exact P value are indicated in the figures. The data in F,H,I are expressed as the means ± s.e.m; ordinary two-way ANOVA followed by Tukey's multiple comparisons test (F) or Sidak's multiple comparisons test (H,I); exact P value are indicated in the ...
Sex differences in ME and LGCI are associated with sexual dimorphism in MS We found that relative to males (n = 11), female mice (n = 11) had significantly lower levels of markers of WD-induced obesity, including gross appearance of mice, intra-abdominal and gonadal fat distributi...
level upon fasting, not seen in females (Fig.3A and Supplementary Fig.1D). These effects were also evident with the selective ERα ligand PPT (Fig.3A). Thus, our experimental set-up confirms that exogenous E2 via ERα impacts obesity, fasting glucose, total fat and VAT ratios in males....
While in males and females the ER-α appears to have an upregulating effect on the cortical and trabecular bone mass, the ER-β accounts for a modulation of the ER-α which predominantly affects females [52]. Though the mechanisms responsible are highly complex, it is safe to say that ...
There are limited numbers of studies investigating SERM treatment in males. Raloxifene treatment improved BMD and decreased fracture in male patients with gonadal suppression therapy due to prostate cancer42. Raloxifene treatment prevented bone loss in orchidectomized rats43. There has been no ...
Glioblastomas (GBM), deadly brain tumors, have greater incidence in males than females. Epidemiological evidence supports a tumor suppressive role of estrogen; however, estrogen as a potential therapy for GBM is limited due to safety concerns. Since GBM express ERβ, a second receptor for estrogen...