Low estrogen doses are effective to keep estradiol and testosterone serum levels at normal premenopausal women in male-to-female transsexualsFl�via Siqueira Cunha
Testosterone, through 5α-reductase activity, becomes dihydrotestosterone, mainly active for sexual differentiation of the male genitalia during embryogenesis, maturation of external testicle's structures and functions. • Estradiol is the main estrogen that maintains the integrity, growth and maturation of...
et al. Efficacy and tolerability of a new estradiol delivering matrix patch (Estraderm MX) in postmenopausal women. Maturitas.2000;34:47-55.http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&Dopt=r&uid=entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10687882&dopt=...
Crystalline progesterone is poorly absorbed and the micronization process increases the absorption of progesterone but first-pass hepatic metabolism is high (Shoham and Kopernik, 2004). Thus, high doses of micronized 17β-estradiol and progesterone are required to achieve therapeutic serum levels. ...
Because of these risks, estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.Delestrogen Description DELESTROGEN® (estradiol valerate injection, USP) contains estradiol ...
The present paper describes the effect of three 17-β-estradiol (E 2) doses (1, 10 and 500 ng E 2/kg) on the cytosolic and nuclear estrogen receptor content of anterior pituitary (Ap) of ovariectomized rats. The estrogen receptors were measured by [ 3h]E 2 exchange in cytosol and cru...
dominant estrogenic activity phase of three daily doses of an estrogen equivalent to 1 mg per day of 17 beta -estradiol per day and a dominant progestagenic activity phase of a combination of an estrogen and a progestogen equivalent to 90 mu g per day of norgestimate; hot flushes...
doses or an equivalent thereof, of a substance exhibiting estrogenic activity equivalent to about 1 mg per day of 17β-estradiol, and a relatively dominant progestogenic activity phase comprising three daily doses or an equivalent thereof, of a combination of a substance exhibiting estrogenic ...
▪Indications and Dosages: Prostate cancer: IM (estradiol valerate) 30 mg or more q1-2 wk. PO 10 mg 3 times a day for at least 3 mo. Breast cancer: PO 10 mg 3 times a day for at least 3 mo. Osteoporosis prophylaxis in postmenopausal females: PO 0.5 mg/day cyclically (3 weeks...
(NCT04539626) will have the objective to evaluate the effect of additional estradiol estrogen therapy on clinical response and mortality in nonsevere COVID-19 patients. Finally, a clinical trial will investigate the change in men’s clinical status with COVID-19 hospitalized and treated with oral...