DanielaInstituteStanikovaInstituteTobiasInstituteLuckInstituteYoonInstituteJuInstituteBaeInstituteJoachimInstituteThieryInstituteUtaInstitutePsychoneuroendocrinology: An International JournalStanikova D,Luck T,Bae YJ,et al. Increased estrogen level can be associated with depression in males[J]. Psychoneuroendocrinology...
The relationship between circulating estradiol and thyroid autoimmunity in males. European Journal of Endocrinology. 2013;170(1):63-7. doi:10.1530/EJE-13-0455. Artini PG, Uccelli A, Papini F, Simi G, Di Berardino OM, Ruggiero M, Cela V. Infertility and pregnancy loss in euthroid women ...
Blood estrogen levelsalso rise slightly in males before and during puberty. The source of these estrogens is probably theSertoli cellsof thetestes(seeChapter 4). The presence of estrogens in males near puberty explains why some pubertal males exhibit slight growth of themammary glands(gynecomastia)...
the level of estrogens in women’s blood rises to 70–80 μg/las a result of the marked intensification of the biosynthesis of the hormone in the placenta. Estrogens cause thickening of the epithelium of the vaginal mucosa, an increase in the weight of the uterus, the rhythmic contraction ...
To assess the effect of altered estrogen to androgen levels on immune system in males in vivo, we selected the established AROM+ mouse model11,12. In this model, human aromatase is ubiquitously expressed, resulting in elevated endogenous levels of estradiol and reduced level of testosterone, and...
drinking cow's milk were measured and used as a baseline, but there was no group which did not drink milk as a control to eliminate the effects of drinking 1 litre of liquid in 10 minutes. The level of estrogen and other hormones in the urine and serum of the participants were measured...
In young adult gonadal intact mice, there was no difference between S122A and WT mice in the mRNA expression level of ERα measured in cortical bone (Table 1). Serum levels of testosterone and DHT, measured by GC–MS/MS, were not altered in S122A males compared to WT littermates, demo...
while in control mice, it downregulated the BMPR2 protein level and inhibited its signaling pathway [41]. This effect may be regulated by 16α-OHE-mediated activation of lysosomes in a nontranscriptional manner [41,48]. In PASMCs, this can further diminish canonical and noncanonical BMPR2 signa...
For this reason, the physiological effects of a disruption of estrogen signaling are initiated at the gene expression level, which can be measured using transcriptomic methods. The widespread prevalence of EDCs in the environment, and particularly their effect on vulnerable populations and sensitive ...
Estrogen appears to regulate Aβ levels at least in part by promoting the non-amyloidogenic cleavage of APP, precluding production of the Aβ peptide. In the human kidney 293 cell line, E2 has been shown to reduce the level of Aβ peptide in a concentration-dependent manner [59]. Further...