estrone and estriol. While it is largely considered a female hormone, estrogen is also produced in males, though in smaller quantities. In women, estrogen is synthesized primarily by the ovaries, but can also be produced by the adrenal glands and fat tissue. While in men, estrogen is mainly...
Total estradiol levels, <5pg/ml were associated with a 2.5-fold increase in hip and vertebral fractures in older women, an association that was independent of age and body weight. Similar associations were found in men. Despite the lower BMD and higher fracture risk in hypogonadal men, there...
Estrogen is a hormone that plays an important role in both men and women. In men, estrogen is responsible for maintaining reproductive health, producing testosterone, and regulating moods. Too much estrogen can cause several health problems in men, so it’s important to know the symptoms and ta...
bronchoconstriction in women with asthma [16], while testosterone may have protective effects in men [17]. Sex differences have also been observed in cystic fibrosis (CF) and bronchiectasis with females having more severe pulmonary inflammation and more frequent and virulent bacterial infections than ...
Ovarian-derived estrogen can signal non-canonically at membrane-associated receptors in the brain to rapidly regulate neuronal function. Early alcohol drinking confers greater risk for alcohol use disorder in women than men, and binge alcohol drinking is correlated with high estrogen levels, but a cau...
Women are twice as likely to develop anxiety or depressive disorders compared to men. Women's increased vulnerability to depressive disorders typically occurs between the beginning of puberty and the age of 55, in concert with estrogen level changes. In addition, it is believed that about 95% ...
The purpose of this study was to quantify the various sources of () and 17 beta-() production in normal men and in women with . The mean production rate of in four young adult men was 58 micrograms/24 h, while that of was 44 micrograms/24 h. In these men, production could be acco...
Arthritis is the leading cause of physical disability in the USA and osteoarthritis (OA), the most common form, affects nearly 27 million people. Women have a higher prevalence of OA than men, but the underlying causes for the increased susceptibility of women to OA are not fully understood....
Identification of sex-based immunoregulatory differences and mechanisms of hormonal immunomodulation would be of potential benefit to both women and men as it would provide a better understanding of immunity and probable autoimmune disease pathogenesis as well as a basis for incisive in vivo investigations...
Estriol [E2] is a most active form of estrogen steroid molecule that has been found to be a clinically significant; however, compared with the female gender, E2 level in men is still above that found in postmenopausal women [29,30] and is able to carry out the endocrine and autocrine ...